Occurrence of Candida albicans in Periodontitis

Background. Periodontal diseases are the result of an imbalance between the microbiota and immune defense. The role of yeast in the pathogenesis of these diseases has been studied. This study aims to assess the occurrence of Candida albicans in periodontitis. Materials and Methods. Fifty subjects we...

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Main Authors: Brahim Jabri, Maryem Iken, Mohamed Achmit, Sana Rida, Oum Keltoum Ennibi
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:International Journal of Dentistry
Online Access:http://dx.doi.org/10.1155/2021/5589664
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author Brahim Jabri
Maryem Iken
Mohamed Achmit
Sana Rida
Oum Keltoum Ennibi
author_facet Brahim Jabri
Maryem Iken
Mohamed Achmit
Sana Rida
Oum Keltoum Ennibi
author_sort Brahim Jabri
collection DOAJ
description Background. Periodontal diseases are the result of an imbalance between the microbiota and immune defense. The role of yeast in the pathogenesis of these diseases has been studied. This study aims to assess the occurrence of Candida albicans in periodontitis. Materials and Methods. Fifty subjects were recruited for the study (15 healthy individuals and 35 periodontitis subjects). The periodontal examination and plaque sampling were carried out for all patients. Candida albicans identification was based on culture, direct examination, and polymerase chain reaction. The statistical analysis was performed by SPSS 20 (SPSS Inc., Chicago, IL, USA). Results. Twenty percent of the diseased group harbored Candida albicans which was slightly higher than in the healthy group (7%), suggesting that, under normal conditions, yeast does not grow easily in subgingival sites. However, no significant difference between the healthy and periodontitis groups (p=0.23) was found. Our results also indicated that the presence of Candida albicans was neither gender nor age related in the studied groups. Conclusion. The results of this study suggest that Candida albicans occurs in periodontitis. More studies are needed to clarify the potential role of this yeast in different stages and forms of the disease.
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spelling doaj-art-eff3c7c3c9624e0984f7f4a2da8009cb2025-08-20T03:21:19ZengWileyInternational Journal of Dentistry1687-87281687-87362021-01-01202110.1155/2021/55896645589664Occurrence of Candida albicans in PeriodontitisBrahim Jabri0Maryem Iken1Mohamed Achmit2Sana Rida3Oum Keltoum Ennibi4Research Laboratory in Oral Biology and Biotechnology, Faculty of Dental Medicine of Rabat, Mohammed V University in Rabat, Rabat, MoroccoClinical Biology Department, Faculty of Medicine and Pharmacy, Mohammed V University in Rabat, Rabat, MoroccoLaboratory of Virology, Microbiology and Quality/ Eco-toxicology and Biodiversity, Faculty of Sciences and Techniques Mohammedia, University Hassan II Casablanca, Casablanca, MoroccoDepartment of Conservative Dentistry, Faculty of Dental Medicine of Rabat, Mohammed V University in Rabat, Rabat, MoroccoDepartment of Periodontology, Faculty of Dental Medicine of Rabat, Mohammed V University in Rabat, Rabat, MoroccoBackground. Periodontal diseases are the result of an imbalance between the microbiota and immune defense. The role of yeast in the pathogenesis of these diseases has been studied. This study aims to assess the occurrence of Candida albicans in periodontitis. Materials and Methods. Fifty subjects were recruited for the study (15 healthy individuals and 35 periodontitis subjects). The periodontal examination and plaque sampling were carried out for all patients. Candida albicans identification was based on culture, direct examination, and polymerase chain reaction. The statistical analysis was performed by SPSS 20 (SPSS Inc., Chicago, IL, USA). Results. Twenty percent of the diseased group harbored Candida albicans which was slightly higher than in the healthy group (7%), suggesting that, under normal conditions, yeast does not grow easily in subgingival sites. However, no significant difference between the healthy and periodontitis groups (p=0.23) was found. Our results also indicated that the presence of Candida albicans was neither gender nor age related in the studied groups. Conclusion. The results of this study suggest that Candida albicans occurs in periodontitis. More studies are needed to clarify the potential role of this yeast in different stages and forms of the disease.http://dx.doi.org/10.1155/2021/5589664
spellingShingle Brahim Jabri
Maryem Iken
Mohamed Achmit
Sana Rida
Oum Keltoum Ennibi
Occurrence of Candida albicans in Periodontitis
International Journal of Dentistry
title Occurrence of Candida albicans in Periodontitis
title_full Occurrence of Candida albicans in Periodontitis
title_fullStr Occurrence of Candida albicans in Periodontitis
title_full_unstemmed Occurrence of Candida albicans in Periodontitis
title_short Occurrence of Candida albicans in Periodontitis
title_sort occurrence of candida albicans in periodontitis
url http://dx.doi.org/10.1155/2021/5589664
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