TSH-Secreting Pituitary Macroadenoma in a Girl with Lingual Thyroid
Patients with long-standing hypothyroid are, in some cases, reported to develop pituitary gland hyperplasia due to loss of feedback inhibition of thyroxine in hypothalamus—the condition of which typically regresses after thyroxine replacement. Herein, a 15-year-old girl—with long-standing untreated...
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | Case Reports in Endocrinology |
| Online Access: | http://dx.doi.org/10.1155/2013/570847 |
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| author | S. Wacharasindhu S. Shuangshoti S. Sunthornyothin |
| author_facet | S. Wacharasindhu S. Shuangshoti S. Sunthornyothin |
| author_sort | S. Wacharasindhu |
| collection | DOAJ |
| description | Patients with long-standing hypothyroid are, in some cases, reported to develop pituitary gland hyperplasia due to loss of feedback inhibition of thyroxine in hypothalamus—the condition of which typically regresses after thyroxine replacement. Herein, a 15-year-old girl—with long-standing untreated lingual hypothyroid—presents with a pathologically proven TSH pituitary macroadenoma and bilateral large ovarian cysts. Although MR imaging may differentiate between hyperplasia and macroadenoma of the pituitary gland, pathological examination is still a cornerstone to correct diagnosis. |
| format | Article |
| id | doaj-art-efeff7afecc44c44a6eb40efd16f61c6 |
| institution | OA Journals |
| issn | 2090-6501 2090-651X |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Endocrinology |
| spelling | doaj-art-efeff7afecc44c44a6eb40efd16f61c62025-08-20T02:22:03ZengWileyCase Reports in Endocrinology2090-65012090-651X2013-01-01201310.1155/2013/570847570847TSH-Secreting Pituitary Macroadenoma in a Girl with Lingual ThyroidS. Wacharasindhu0S. Shuangshoti1S. Sunthornyothin2Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, Bangkok 10330, ThailandDepartment of Pathology and Chulalongkorn GenePRO Center, Faculty of Medicine, Chulalongkorn University, Bangkok 10330, ThailandDepartment of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok 10330, ThailandPatients with long-standing hypothyroid are, in some cases, reported to develop pituitary gland hyperplasia due to loss of feedback inhibition of thyroxine in hypothalamus—the condition of which typically regresses after thyroxine replacement. Herein, a 15-year-old girl—with long-standing untreated lingual hypothyroid—presents with a pathologically proven TSH pituitary macroadenoma and bilateral large ovarian cysts. Although MR imaging may differentiate between hyperplasia and macroadenoma of the pituitary gland, pathological examination is still a cornerstone to correct diagnosis.http://dx.doi.org/10.1155/2013/570847 |
| spellingShingle | S. Wacharasindhu S. Shuangshoti S. Sunthornyothin TSH-Secreting Pituitary Macroadenoma in a Girl with Lingual Thyroid Case Reports in Endocrinology |
| title | TSH-Secreting Pituitary Macroadenoma in a Girl with Lingual Thyroid |
| title_full | TSH-Secreting Pituitary Macroadenoma in a Girl with Lingual Thyroid |
| title_fullStr | TSH-Secreting Pituitary Macroadenoma in a Girl with Lingual Thyroid |
| title_full_unstemmed | TSH-Secreting Pituitary Macroadenoma in a Girl with Lingual Thyroid |
| title_short | TSH-Secreting Pituitary Macroadenoma in a Girl with Lingual Thyroid |
| title_sort | tsh secreting pituitary macroadenoma in a girl with lingual thyroid |
| url | http://dx.doi.org/10.1155/2013/570847 |
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