Adsorption of Atenolol on Talc: An Indication of Drug Interference with an Excipient
Talc is commonly used as an excipient for drug formulations. The general expectation is that the excipient should have only minimal interactions with the carrying drug. In this study, the adsorption of atenolol (AT), a β-blocker, on talc, a clay mineral of pH-dependent surface charge, was evaluated...
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Main Authors: | Zhaohui Li, Nicole M. Fitzgerald, Guocheng Lv, Wei-Teh Jiang, Limei Wu |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2015-04-01
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Series: | Adsorption Science & Technology |
Online Access: | https://doi.org/10.1260/0263-6174.33.4.379 |
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