Psychiatric Comorbidities in Adults with Epilepsy: A Systematic Review
Epilepsy is a chronic neurological condition that is highly predisposed to a variety of mental health problems. This systematic literature review identified original research articles that reported the prevalence of psychiatric comorbidities based on clinical assessments amongst patients with epilep...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2025-07-01
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| Series: | Preventive Medicine: Research & Reviews |
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| Online Access: | https://journals.lww.com/10.4103/PMRR.PMRR_38_24 |
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| author | Arun Murugan S Geethanjali M. R. Jeevapriya G. Pavithra OL Athira K. Sathishkumar |
| author_facet | Arun Murugan S Geethanjali M. R. Jeevapriya G. Pavithra OL Athira K. Sathishkumar |
| author_sort | Arun Murugan |
| collection | DOAJ |
| description | Epilepsy is a chronic neurological condition that is highly predisposed to a variety of mental health problems. This systematic literature review identified original research articles that reported the prevalence of psychiatric comorbidities based on clinical assessments amongst patients with epilepsy (PWE). The included articles were published from 2000 to 2022 and focused on adults aged ≥18 years who had psychiatric diagnoses. The primary outcome was the prevalence of psychiatric comorbidities amongst PWE. A modified Newcastle–Ottawa Scale was used to assess the quality of the studies. Thirty-three articles were reviewed in full-text screening. Out of these, 15 articles that were consistent with the inclusion criteria were included in our systematic review. This protocol was registered in PROSPERO with registration ID CRD42023461739. General Anxiety Disorder and Major Depressive Disorder were the most common psychiatric comorbidities, with prevalence rates of 20.14% and 23.94%, respectively. Other reported comorbidities included post-traumatic stress disorder (8.3%), obsessive–compulsive disorder (2.9%), bipolar disorder (7.1%), psychosis (8.2%) and phobia (18.25%). These findings suggest that screening tools for depression and anxiety should be included as part of the training for epilepsy care. |
| format | Article |
| id | doaj-art-efe6e416febb4f80b67a03088953cdf8 |
| institution | Kabale University |
| issn | 2950-5828 2950-5836 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Preventive Medicine: Research & Reviews |
| spelling | doaj-art-efe6e416febb4f80b67a03088953cdf82025-08-20T03:31:06ZengWolters Kluwer Medknow PublicationsPreventive Medicine: Research & Reviews2950-58282950-58362025-07-012417317710.4103/PMRR.PMRR_38_24Psychiatric Comorbidities in Adults with Epilepsy: A Systematic ReviewArun MuruganS GeethanjaliM. R. JeevapriyaG. PavithraOL AthiraK. SathishkumarEpilepsy is a chronic neurological condition that is highly predisposed to a variety of mental health problems. This systematic literature review identified original research articles that reported the prevalence of psychiatric comorbidities based on clinical assessments amongst patients with epilepsy (PWE). The included articles were published from 2000 to 2022 and focused on adults aged ≥18 years who had psychiatric diagnoses. The primary outcome was the prevalence of psychiatric comorbidities amongst PWE. A modified Newcastle–Ottawa Scale was used to assess the quality of the studies. Thirty-three articles were reviewed in full-text screening. Out of these, 15 articles that were consistent with the inclusion criteria were included in our systematic review. This protocol was registered in PROSPERO with registration ID CRD42023461739. General Anxiety Disorder and Major Depressive Disorder were the most common psychiatric comorbidities, with prevalence rates of 20.14% and 23.94%, respectively. Other reported comorbidities included post-traumatic stress disorder (8.3%), obsessive–compulsive disorder (2.9%), bipolar disorder (7.1%), psychosis (8.2%) and phobia (18.25%). These findings suggest that screening tools for depression and anxiety should be included as part of the training for epilepsy care.https://journals.lww.com/10.4103/PMRR.PMRR_38_24epilepsypsychiatric comorbiditiesprimary healthcaresystematic review |
| spellingShingle | Arun Murugan S Geethanjali M. R. Jeevapriya G. Pavithra OL Athira K. Sathishkumar Psychiatric Comorbidities in Adults with Epilepsy: A Systematic Review Preventive Medicine: Research & Reviews epilepsy psychiatric comorbidities primary healthcare systematic review |
| title | Psychiatric Comorbidities in Adults with Epilepsy: A Systematic Review |
| title_full | Psychiatric Comorbidities in Adults with Epilepsy: A Systematic Review |
| title_fullStr | Psychiatric Comorbidities in Adults with Epilepsy: A Systematic Review |
| title_full_unstemmed | Psychiatric Comorbidities in Adults with Epilepsy: A Systematic Review |
| title_short | Psychiatric Comorbidities in Adults with Epilepsy: A Systematic Review |
| title_sort | psychiatric comorbidities in adults with epilepsy a systematic review |
| topic | epilepsy psychiatric comorbidities primary healthcare systematic review |
| url | https://journals.lww.com/10.4103/PMRR.PMRR_38_24 |
| work_keys_str_mv | AT arunmurugan psychiatriccomorbiditiesinadultswithepilepsyasystematicreview AT sgeethanjali psychiatriccomorbiditiesinadultswithepilepsyasystematicreview AT mrjeevapriya psychiatriccomorbiditiesinadultswithepilepsyasystematicreview AT gpavithra psychiatriccomorbiditiesinadultswithepilepsyasystematicreview AT olathira psychiatriccomorbiditiesinadultswithepilepsyasystematicreview AT ksathishkumar psychiatriccomorbiditiesinadultswithepilepsyasystematicreview |