Using an objective computer task (QbTest) to aid the identification of attention deficit hyperactivity disorder (ADHD) in the Children and Young People Secure Estate (CYPSE): a feasibility randomised controlled trial
Objectives QbTest has been shown to improve time to decision/diagnosis for young people with attention deficit hyperactivity disorder (ADHD). The aim was to assess the feasibility of QbTest for young people in prison.Design Single-centre feasibility randomised controlled trial (RCT), with 1:1 alloca...
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BMJ Publishing Group
2022-12-01
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| Series: | BMJ Open |
| Online Access: | https://bmjopen.bmj.com/content/12/12/e064951.full |
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| author | Charlotte Lucy Hall Bryony Beresford Prathiba Chitsabesan Charlotte Lennox Lesley-Anne Carter Susan Young Abdullah Kraam Lloyd Wilkinson-Cunningham Mindy Reeves Vaseem Mohammed Sally Trowse |
| author_facet | Charlotte Lucy Hall Bryony Beresford Prathiba Chitsabesan Charlotte Lennox Lesley-Anne Carter Susan Young Abdullah Kraam Lloyd Wilkinson-Cunningham Mindy Reeves Vaseem Mohammed Sally Trowse |
| author_sort | Charlotte Lucy Hall |
| collection | DOAJ |
| description | Objectives QbTest has been shown to improve time to decision/diagnosis for young people with attention deficit hyperactivity disorder (ADHD). The aim was to assess the feasibility of QbTest for young people in prison.Design Single-centre feasibility randomised controlled trial (RCT), with 1:1 allocation. Concealed random allocation using an online pseudorandom list with random permuted blocks of varying sizes.Setting One Young Offenders Institution in England.Participants 355 young people aged 15–18 years displaying possible symptoms of ADHD were assessed for eligibility, 69 were eligible to take part and 60 were randomised.Intervention QbTest—a computer task measuring attention, activity and impulsivity.Main outcome measures Eligibility, recruitment and retention rates and acceptability of randomisation and trial participation.Results Of the 355 young people assessed for eligibility, 69 were eligible and 60 were randomised (n=30 QbTest plus usual care; n=30 usual care alone). The study achieved the specified recruitment target. Trial participation and randomisation were deemed acceptable by the majority of participants. 78% of young people were followed up at 3 months, but only 32% at 6 months, although this was also affected by COVID-19 restrictions. Secondary outcomes were mixed. Participants including clinical staff were mostly supportive of the study and QbTest; however, some young people found QbTest hard and there were issues with implementation of the ADHD care pathway. There were no serious adverse events secondary to the study or intervention and no one was withdrawn from the study due to an adverse event.Conclusions With adaptations, a fully powered RCT may be achievable to evaluate the effectiveness of QbTest in the assessment of ADHD in the Children and Young People Secure Estate, with time to decision (days) as the primary outcome measure. However, further programme developmental work is required to address some of the challenges highlighted prior to a larger trial.Trial registration number ISRCTN17402196. |
| format | Article |
| id | doaj-art-efe3577474974eb1b15ab9dff0a2cffc |
| institution | DOAJ |
| issn | 2044-6055 |
| language | English |
| publishDate | 2022-12-01 |
| publisher | BMJ Publishing Group |
| record_format | Article |
| series | BMJ Open |
| spelling | doaj-art-efe3577474974eb1b15ab9dff0a2cffc2025-08-20T03:11:21ZengBMJ Publishing GroupBMJ Open2044-60552022-12-01121210.1136/bmjopen-2022-064951Using an objective computer task (QbTest) to aid the identification of attention deficit hyperactivity disorder (ADHD) in the Children and Young People Secure Estate (CYPSE): a feasibility randomised controlled trialCharlotte Lucy Hall0Bryony Beresford1Prathiba Chitsabesan2Charlotte Lennox3Lesley-Anne Carter4Susan Young5Abdullah Kraam6Lloyd Wilkinson-Cunningham7Mindy Reeves8Vaseem Mohammed9Sally Trowse105 NIHR MindTech MedTech Co-operative, Academic Unit of Mental Health & Clinical Neurosciences, Faculty of Medicine & Health Sciences, University of Nottingham, Nottingham, UK2 Social Policy Research Unit, School for Business and Society, University of York, York, UKChildren and Young People`s Research Unit, Pennine Care NHS Foundation Trust, Ashton-under-Lyne, UK1 Division of Psychology and Mental Health, The University of Manchester, Manchester, UK3 Centre for Biostatistics, Division of Population Health, Health Services Research and Primary Care, The University of Manchester, Manchester, UKPhysiotherapy, Aneurin Bevan University Health Board, Newport, UK6 Child and Adolescent Mental Health Service, Rotherham Doncaster and South Humber Mental Health NHS Foundation Trust, Doncaster, UK8 Research and Development, Leeds Community Healthcare NHS Trust, Leeds, UK9 Medical School, The University of Manchester, Manchester, UKMedical School, The University of Manchester, Manchester, UKChild and Adolescent Mental Health Service, Pennine Care NHS Foundation Trust, Ashton-under-Lyne, UKObjectives QbTest has been shown to improve time to decision/diagnosis for young people with attention deficit hyperactivity disorder (ADHD). The aim was to assess the feasibility of QbTest for young people in prison.Design Single-centre feasibility randomised controlled trial (RCT), with 1:1 allocation. Concealed random allocation using an online pseudorandom list with random permuted blocks of varying sizes.Setting One Young Offenders Institution in England.Participants 355 young people aged 15–18 years displaying possible symptoms of ADHD were assessed for eligibility, 69 were eligible to take part and 60 were randomised.Intervention QbTest—a computer task measuring attention, activity and impulsivity.Main outcome measures Eligibility, recruitment and retention rates and acceptability of randomisation and trial participation.Results Of the 355 young people assessed for eligibility, 69 were eligible and 60 were randomised (n=30 QbTest plus usual care; n=30 usual care alone). The study achieved the specified recruitment target. Trial participation and randomisation were deemed acceptable by the majority of participants. 78% of young people were followed up at 3 months, but only 32% at 6 months, although this was also affected by COVID-19 restrictions. Secondary outcomes were mixed. Participants including clinical staff were mostly supportive of the study and QbTest; however, some young people found QbTest hard and there were issues with implementation of the ADHD care pathway. There were no serious adverse events secondary to the study or intervention and no one was withdrawn from the study due to an adverse event.Conclusions With adaptations, a fully powered RCT may be achievable to evaluate the effectiveness of QbTest in the assessment of ADHD in the Children and Young People Secure Estate, with time to decision (days) as the primary outcome measure. However, further programme developmental work is required to address some of the challenges highlighted prior to a larger trial.Trial registration number ISRCTN17402196.https://bmjopen.bmj.com/content/12/12/e064951.full |
| spellingShingle | Charlotte Lucy Hall Bryony Beresford Prathiba Chitsabesan Charlotte Lennox Lesley-Anne Carter Susan Young Abdullah Kraam Lloyd Wilkinson-Cunningham Mindy Reeves Vaseem Mohammed Sally Trowse Using an objective computer task (QbTest) to aid the identification of attention deficit hyperactivity disorder (ADHD) in the Children and Young People Secure Estate (CYPSE): a feasibility randomised controlled trial BMJ Open |
| title | Using an objective computer task (QbTest) to aid the identification of attention deficit hyperactivity disorder (ADHD) in the Children and Young People Secure Estate (CYPSE): a feasibility randomised controlled trial |
| title_full | Using an objective computer task (QbTest) to aid the identification of attention deficit hyperactivity disorder (ADHD) in the Children and Young People Secure Estate (CYPSE): a feasibility randomised controlled trial |
| title_fullStr | Using an objective computer task (QbTest) to aid the identification of attention deficit hyperactivity disorder (ADHD) in the Children and Young People Secure Estate (CYPSE): a feasibility randomised controlled trial |
| title_full_unstemmed | Using an objective computer task (QbTest) to aid the identification of attention deficit hyperactivity disorder (ADHD) in the Children and Young People Secure Estate (CYPSE): a feasibility randomised controlled trial |
| title_short | Using an objective computer task (QbTest) to aid the identification of attention deficit hyperactivity disorder (ADHD) in the Children and Young People Secure Estate (CYPSE): a feasibility randomised controlled trial |
| title_sort | using an objective computer task qbtest to aid the identification of attention deficit hyperactivity disorder adhd in the children and young people secure estate cypse a feasibility randomised controlled trial |
| url | https://bmjopen.bmj.com/content/12/12/e064951.full |
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