Rapid and Sensitive Method for Quantitative Determination of Lopinavir and Ritonavir in Human Plasma by Liquid Chromatography- Tandem Mass Specrtometry

Rapid and Sensitive Method for Quantitative Determination of Lopinavir and Ritonavir in Human Plasma by Liquid Chromatography- Tandem Mass Specrtometry

A rapid and sensitive liquid chromatography-mass spectrometric (LC-MS-MS) method for the simultaneous determination of lopinavir and ritonavir in human plasma using abacavir as internal standard has been developed and validated. Sample preparation of plasma involved solid phase extraction. Detection...

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Bibliographic Details
Main Authors:	G. A. Temghare, S. S. Shetye, S. S. Joshi
Format:	Article
Language:	English
Published:	Wiley 2009-01-01
Series:	E-Journal of Chemistry
Online Access:	http://dx.doi.org/10.1155/2009/709478
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