Safe Use of Intraspinal Anesthesia in Geriatric Orthopedic Surgery and Its Effect on Coagulation Factors
Objective This study aimed to observe the safe use of intraspinal anesthesia in geriatric orthopedic surgery and its effect on coagulation factors.Methods The anesthesia indices, cognitive functions, hemodynamic indicators, along with coagulation function indices were compared. The duration of anest...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2024-01-01
|
| Series: | Journal of Investigative Surgery |
| Subjects: | |
| Online Access: | https://www.tandfonline.com/doi/10.1080/08941939.2024.2419138 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850099996554166272 |
|---|---|
| author | Jing Xiang Yi Sun Jingbo Pi |
| author_facet | Jing Xiang Yi Sun Jingbo Pi |
| author_sort | Jing Xiang |
| collection | DOAJ |
| description | Objective This study aimed to observe the safe use of intraspinal anesthesia in geriatric orthopedic surgery and its effect on coagulation factors.Methods The anesthesia indices, cognitive functions, hemodynamic indicators, along with coagulation function indices were compared. The duration of anesthesia was compared between the two groups. Adverse reactions occurring in the two groups of patients were compared.Results The time to awaken, time to open eyes, time to the verbal statement, the onset of anesthesia, duration of sensory blockade, and duration of motor nerve blockade were shorter while the duration of analgesia was longer in the observation group than in the control group. The observation group’s postoperative Mini-Mental State Examination scores were higher than those of the control group. Heart rate and mean arterial pressure of the patients in the observation group at 10 min after anesthesia and at the end of surgery were lower versus those in the control group. The observation group had lower levels of von Willebrand factor (%) and fibrinogen at 10 min after anesthesia and at the end of surgery than the control group, and lower levels of the thrombin-antithrombin complex at the end of surgery than the control group. The observation group exhibited a lower incidence of adverse reactions in contrast to the control group.Conclusion The application of intraspinal anesthesia in geriatric orthopedic surgery has a significant and remarkable effect, with less impact on patients’ hemodynamics and postoperative cognitive function, and can improve patients’ blood hypercoagulability. |
| format | Article |
| id | doaj-art-efce6002c69447cc8d9e95951f56332d |
| institution | DOAJ |
| issn | 0894-1939 1521-0553 |
| language | English |
| publishDate | 2024-01-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Journal of Investigative Surgery |
| spelling | doaj-art-efce6002c69447cc8d9e95951f56332d2025-08-20T02:40:23ZengTaylor & Francis GroupJournal of Investigative Surgery0894-19391521-05532024-01-0137110.1080/08941939.2024.2419138Safe Use of Intraspinal Anesthesia in Geriatric Orthopedic Surgery and Its Effect on Coagulation FactorsJing Xiang0Yi Sun1Jingbo Pi2Department of Anesthesia, Hospital of Dongnan District, Chongqing, ChinaDepartment of Oncology, People’s Hospital of Guizhou Province, Guiyang, Guizhou Province, ChinaDepartment of Anesthesia, Second People’s Hospital of Banan District, Chongqing, ChinaObjective This study aimed to observe the safe use of intraspinal anesthesia in geriatric orthopedic surgery and its effect on coagulation factors.Methods The anesthesia indices, cognitive functions, hemodynamic indicators, along with coagulation function indices were compared. The duration of anesthesia was compared between the two groups. Adverse reactions occurring in the two groups of patients were compared.Results The time to awaken, time to open eyes, time to the verbal statement, the onset of anesthesia, duration of sensory blockade, and duration of motor nerve blockade were shorter while the duration of analgesia was longer in the observation group than in the control group. The observation group’s postoperative Mini-Mental State Examination scores were higher than those of the control group. Heart rate and mean arterial pressure of the patients in the observation group at 10 min after anesthesia and at the end of surgery were lower versus those in the control group. The observation group had lower levels of von Willebrand factor (%) and fibrinogen at 10 min after anesthesia and at the end of surgery than the control group, and lower levels of the thrombin-antithrombin complex at the end of surgery than the control group. The observation group exhibited a lower incidence of adverse reactions in contrast to the control group.Conclusion The application of intraspinal anesthesia in geriatric orthopedic surgery has a significant and remarkable effect, with less impact on patients’ hemodynamics and postoperative cognitive function, and can improve patients’ blood hypercoagulability.https://www.tandfonline.com/doi/10.1080/08941939.2024.2419138Intraspinal anesthesiageriatric orthopedic surgerycoagulation factorssafe usecognitive function |
| spellingShingle | Jing Xiang Yi Sun Jingbo Pi Safe Use of Intraspinal Anesthesia in Geriatric Orthopedic Surgery and Its Effect on Coagulation Factors Journal of Investigative Surgery Intraspinal anesthesia geriatric orthopedic surgery coagulation factors safe use cognitive function |
| title | Safe Use of Intraspinal Anesthesia in Geriatric Orthopedic Surgery and Its Effect on Coagulation Factors |
| title_full | Safe Use of Intraspinal Anesthesia in Geriatric Orthopedic Surgery and Its Effect on Coagulation Factors |
| title_fullStr | Safe Use of Intraspinal Anesthesia in Geriatric Orthopedic Surgery and Its Effect on Coagulation Factors |
| title_full_unstemmed | Safe Use of Intraspinal Anesthesia in Geriatric Orthopedic Surgery and Its Effect on Coagulation Factors |
| title_short | Safe Use of Intraspinal Anesthesia in Geriatric Orthopedic Surgery and Its Effect on Coagulation Factors |
| title_sort | safe use of intraspinal anesthesia in geriatric orthopedic surgery and its effect on coagulation factors |
| topic | Intraspinal anesthesia geriatric orthopedic surgery coagulation factors safe use cognitive function |
| url | https://www.tandfonline.com/doi/10.1080/08941939.2024.2419138 |
| work_keys_str_mv | AT jingxiang safeuseofintraspinalanesthesiaingeriatricorthopedicsurgeryanditseffectoncoagulationfactors AT yisun safeuseofintraspinalanesthesiaingeriatricorthopedicsurgeryanditseffectoncoagulationfactors AT jingbopi safeuseofintraspinalanesthesiaingeriatricorthopedicsurgeryanditseffectoncoagulationfactors |