Gut microbiota and protein-to-protein ratios in NAFLD: insights from Mendelian randomization and murine studies

Gut microbiota and protein-to-protein ratios in NAFLD: insights from Mendelian randomization and murine studies

BackgroundGut microbiota and protein metabolism play critical roles in non-alcoholic fatty liver disease (NAFLD) progression, but their causal relationships remain unclear. This study integrates Mendelian randomization (MR) analysis and experimental validation to identify microbial and molecular con...

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Main Authors: Langhuan Lei, Wei Shi, Xing Yang, Jiali Lin, Qiuyu Liang, Xiaozhi Huang, Liuxian Pan, Wei Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Nutrition
Subjects:
gut microbiota
protein-to-protein ratios
NAFLD
Mendelian randomization
Lactobacillus salivarius
Online Access:https://www.frontiersin.org/articles/10.3389/fnut.2025.1597390/full
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