Spontaneous and activation-induced apoptosis of peripheral blood mononuclear cells in the pathogenesis of type 1 diabetes mellitus

Spontaneous and activation-induced apoptosis of peripheral blood mononuclear cells in the pathogenesis of type 1 diabetes mellitus

Apoptosis is the leading mechanism of pancreatic β-cell destruction in type 1 diabetes mellitus (T1DM). Assessment of activation apoptosis in response to stimulation with mitogen or a specific antigen is considered more significant when studying apoptosis markers in peripheral blood mononuclear cell...

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Bibliographic Details
Main Authors: A. V. Lugovaya, N. M. Kalinina, V. Ph. Mitreikin, Yu. V. Emanuel, Yu. P. Kovalchuk, A. V. Artyomova
Format: Article
Language:Russian
Published: St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists 2020-01-01
Series:Медицинская иммунология
Subjects:
apoptosis
t lymphocytes
phytohaemagglutinin
insulin
type 1 diabetes mellitus
c-peptide
β-cell
Online Access:https://www.mimmun.ru/mimmun/article/view/1834
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