Long COVID Is Associated with Decreased Quality of Life and Increased Mental Disability

COVID-19’s impact on quality of life (QoL) has been studied; however, data on the effects of long COVID on QoL and mental disability remain limited. This study aimed to investigate whether long COVID is associated with decreased QoL and increased mental disability. We analyzed data from adults (≥18...

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Main Authors: Jaewhan Kim, Emeka Elvis Duru, Peter Weir, Sanghoon Lee
Format: Article
Language:English
Published: MDPI AG 2024-10-01
Series:COVID
Subjects:
Online Access:https://www.mdpi.com/2673-8112/4/11/120
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author Jaewhan Kim
Emeka Elvis Duru
Peter Weir
Sanghoon Lee
author_facet Jaewhan Kim
Emeka Elvis Duru
Peter Weir
Sanghoon Lee
author_sort Jaewhan Kim
collection DOAJ
description COVID-19’s impact on quality of life (QoL) has been studied; however, data on the effects of long COVID on QoL and mental disability remain limited. This study aimed to investigate whether long COVID is associated with decreased QoL and increased mental disability. We analyzed data from adults (≥18 years) in the 2022 Medical Expenditure Panel Survey (MEPS). Physical and mental QoL were assessed using the Veterans RAND 12-Item Health Survey, while mental disability was measured with the Kessler Index. Long COVID was defined as experiencing COVID-related symptoms for over 3 months. To account for skewness in the outcome variables, the study employed survey-weighted generalized linear regression with a log link and gamma distribution. The analysis included 153,330,408 subjects (unweighted n = 10,975). The average age of those with and without long COVID was similar (51 vs. 52 years, <i>p</i> = 0.46). Subjects with long COVID had a 3% lower physical QoL (β = −0.03, <i>p</i> = 0.02), a 4% lower mental QoL (β = −0.04, <i>p</i> < 0.01), and a 26% higher mental disability score (β = 0.26, <i>p</i> < 0.01) compared to those without long COVID. These findings highlight the urgent need for targeted strategies to address long COVID and support patients in recovering their pre-COVID QoL and mental health.
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spelling doaj-art-efc417930f48411795ab8193bf4d658c2025-08-20T02:08:14ZengMDPI AGCOVID2673-81122024-10-014111719173010.3390/covid4110120Long COVID Is Associated with Decreased Quality of Life and Increased Mental DisabilityJaewhan Kim0Emeka Elvis Duru1Peter Weir2Sanghoon Lee3Department of Physical Therapy, University of Utah, 520 Wakara Way, Salt Lake City, UT 84108, USADepartment of Pharmacotherapy, University of Utah, 30 South 2000 East, Salt Lake City, UT 84112, USAMedical Group Population Health, University of Utah, 50 North Medical Drive, Salt Lake City, UT 84132, USADepartment of Economics, Hannam University, 70 Hannamro, Daedukgu, Daejeon 34430, Republic of KoreaCOVID-19’s impact on quality of life (QoL) has been studied; however, data on the effects of long COVID on QoL and mental disability remain limited. This study aimed to investigate whether long COVID is associated with decreased QoL and increased mental disability. We analyzed data from adults (≥18 years) in the 2022 Medical Expenditure Panel Survey (MEPS). Physical and mental QoL were assessed using the Veterans RAND 12-Item Health Survey, while mental disability was measured with the Kessler Index. Long COVID was defined as experiencing COVID-related symptoms for over 3 months. To account for skewness in the outcome variables, the study employed survey-weighted generalized linear regression with a log link and gamma distribution. The analysis included 153,330,408 subjects (unweighted n = 10,975). The average age of those with and without long COVID was similar (51 vs. 52 years, <i>p</i> = 0.46). Subjects with long COVID had a 3% lower physical QoL (β = −0.03, <i>p</i> = 0.02), a 4% lower mental QoL (β = −0.04, <i>p</i> < 0.01), and a 26% higher mental disability score (β = 0.26, <i>p</i> < 0.01) compared to those without long COVID. These findings highlight the urgent need for targeted strategies to address long COVID and support patients in recovering their pre-COVID QoL and mental health.https://www.mdpi.com/2673-8112/4/11/120long COVIDquality of lifemental disabilityMEPS
spellingShingle Jaewhan Kim
Emeka Elvis Duru
Peter Weir
Sanghoon Lee
Long COVID Is Associated with Decreased Quality of Life and Increased Mental Disability
COVID
long COVID
quality of life
mental disability
MEPS
title Long COVID Is Associated with Decreased Quality of Life and Increased Mental Disability
title_full Long COVID Is Associated with Decreased Quality of Life and Increased Mental Disability
title_fullStr Long COVID Is Associated with Decreased Quality of Life and Increased Mental Disability
title_full_unstemmed Long COVID Is Associated with Decreased Quality of Life and Increased Mental Disability
title_short Long COVID Is Associated with Decreased Quality of Life and Increased Mental Disability
title_sort long covid is associated with decreased quality of life and increased mental disability
topic long COVID
quality of life
mental disability
MEPS
url https://www.mdpi.com/2673-8112/4/11/120
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AT emekaelvisduru longcovidisassociatedwithdecreasedqualityoflifeandincreasedmentaldisability
AT peterweir longcovidisassociatedwithdecreasedqualityoflifeandincreasedmentaldisability
AT sanghoonlee longcovidisassociatedwithdecreasedqualityoflifeandincreasedmentaldisability