TMCO1, as a potential biomarker of prognosis and immunotherapy response, regulates head and neck squamous cell carcinoma proliferation and migration

TMCO1, as a potential biomarker of prognosis and immunotherapy response, regulates head and neck squamous cell carcinoma proliferation and migration

Abstract Transmembrane and coiled-coil domains 1 (TMCO1), an endoplasmic reticulum transmembrane protein, actively regulates intracellular Ca2+ concentration and is associated with poor prognosis in several cancers. This study shows that TMCO1 is a potential biological prognostic indicator and thera...

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Bibliographic Details
Main Authors: Ting Li, Lu Chen, Guangkai Zhou, Yuhan Deng, Meng Zhou, Mingze Yan, Shuyan Dong, Kaixun Xing, Shan Yu, Hongjiang He
Format: Article
Language:English
Published: Springer 2025-05-01
Series:Discover Oncology
Subjects:
HNSCC
TMCO1
Prognosis
Biomarker
Immunotherapy
Online Access:https://doi.org/10.1007/s12672-025-02437-y
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