The role of neutrophilia in hyperlactatemia, blood acidosis, impaired oxygen transport, and mortality outcome in critically ill COVID-19 patients

The role of neutrophilia in hyperlactatemia, blood acidosis, impaired oxygen transport, and mortality outcome in critically ill COVID-19 patients

IntroductionCOVID-19 severity and high in-hospital mortality are often associated with severe hypoxemia, hyperlactatemia, and acidosis, yet the key players driving this association remain unclear. It is generally assumed that organ damage causes toxic acidosis, but since neutrophil numbers in severe...

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Bibliographic Details
Main Authors: Basma A. Yasseen, Aya A. Elkhodiry, Hajar El-sayed, Mona Zidan, Azza G. Kamel, Mohamed A. Badawy, Marwa S. Hamza, Riem M. El-Messiery, Mohamed El Ansary, Engy A. Abdel-Rahman, Sameh S. Ali
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Molecular Biosciences
Subjects:
lung damage
COVID-19 mortality
neutrophils
lactate
acidosis
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2024.1510592/full
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