In vitro permeation studies of phenolics from horse chestnut seed gels prepared with different polyacrylic acid polymer derivatives
The aim of this study was to investigate the effects of polyacrylic acid polymers (Ultrez 10, Ultrez 20, Carbopol 980, and Carbopol 940) on the viscosity and the in vitro permeation of phenolic compounds from the gel prepared from natural horse chestnut seed extract. Experiments were performed in th...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Sciendo
2015-06-01
|
| Series: | Acta Pharmaceutica |
| Subjects: | |
| Online Access: | https://doi.org/10.1515/acph-2015-0013 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832572518706184192 |
|---|---|
| author | Zelbienė Eglė Draksiene Gailute Savickas Arunas Kopustinskiene Dalia Masteikova Ruta Bernatoniene Jurga |
| author_facet | Zelbienė Eglė Draksiene Gailute Savickas Arunas Kopustinskiene Dalia Masteikova Ruta Bernatoniene Jurga |
| author_sort | Zelbienė Eglė |
| collection | DOAJ |
| description | The aim of this study was to investigate the effects of polyacrylic acid polymers (Ultrez 10, Ultrez 20, Carbopol 980, and Carbopol 940) on the viscosity and the in vitro permeation of phenolic compounds from the gel prepared from natural horse chestnut seed extract. Experiments were performed in the presence and in the absence of peppermint oil (Mentha piperita). Our results showed that peppermint oil decreased the viscosity of the gels and permeation of phenolic compounds from all gel samples. Results show that the highest content of phenolic compounds (1.758 μg cm-2) permeated in vitro from gel based on Carbopol Ultrez 20 without peppermint oil added (p < 0.05 vs. other tested polymers). |
| format | Article |
| id | doaj-art-efbc53423502432eb93f1a128c01fd87 |
| institution | Kabale University |
| issn | 1846-9558 |
| language | English |
| publishDate | 2015-06-01 |
| publisher | Sciendo |
| record_format | Article |
| series | Acta Pharmaceutica |
| spelling | doaj-art-efbc53423502432eb93f1a128c01fd872025-02-02T09:55:40ZengSciendoActa Pharmaceutica1846-95582015-06-0165218118910.1515/acph-2015-0013acph-2015-0013In vitro permeation studies of phenolics from horse chestnut seed gels prepared with different polyacrylic acid polymer derivativesZelbienė Eglė0Draksiene Gailute1Savickas Arunas2Kopustinskiene Dalia3Masteikova Ruta4Bernatoniene Jurga5Lithuanian University of Health Sciences, Medical Academy Faculty of Pharmacy 50009 Kaunas, LithuaniaLithuanian University of Health Sciences, Medical Academy Faculty of Pharmacy 50009 Kaunas, LithuaniaLithuanian University of Health Sciences, Medical Academy Faculty of Pharmacy 50009 Kaunas, LithuaniaLithuanian University of Health Sciences, Medical Academy Faculty of Pharmacy 50009 Kaunas, LithuaniaUniversity of Veterinary and Pharmaceutical Sciences Faculty of Pharmacy 61242 Brno, Czech RepublicLithuanian University of Health Sciences, Medical Academy Faculty of Pharmacy 50009 Kaunas, LithuaniaThe aim of this study was to investigate the effects of polyacrylic acid polymers (Ultrez 10, Ultrez 20, Carbopol 980, and Carbopol 940) on the viscosity and the in vitro permeation of phenolic compounds from the gel prepared from natural horse chestnut seed extract. Experiments were performed in the presence and in the absence of peppermint oil (Mentha piperita). Our results showed that peppermint oil decreased the viscosity of the gels and permeation of phenolic compounds from all gel samples. Results show that the highest content of phenolic compounds (1.758 μg cm-2) permeated in vitro from gel based on Carbopol Ultrez 20 without peppermint oil added (p < 0.05 vs. other tested polymers).https://doi.org/10.1515/acph-2015-0013horse chestnutpolyacrylic acid polymerspermeation |
| spellingShingle | Zelbienė Eglė Draksiene Gailute Savickas Arunas Kopustinskiene Dalia Masteikova Ruta Bernatoniene Jurga In vitro permeation studies of phenolics from horse chestnut seed gels prepared with different polyacrylic acid polymer derivatives Acta Pharmaceutica horse chestnut polyacrylic acid polymers permeation |
| title | In vitro permeation studies of phenolics from horse chestnut seed gels prepared with different polyacrylic acid polymer derivatives |
| title_full | In vitro permeation studies of phenolics from horse chestnut seed gels prepared with different polyacrylic acid polymer derivatives |
| title_fullStr | In vitro permeation studies of phenolics from horse chestnut seed gels prepared with different polyacrylic acid polymer derivatives |
| title_full_unstemmed | In vitro permeation studies of phenolics from horse chestnut seed gels prepared with different polyacrylic acid polymer derivatives |
| title_short | In vitro permeation studies of phenolics from horse chestnut seed gels prepared with different polyacrylic acid polymer derivatives |
| title_sort | in vitro permeation studies of phenolics from horse chestnut seed gels prepared with different polyacrylic acid polymer derivatives |
| topic | horse chestnut polyacrylic acid polymers permeation |
| url | https://doi.org/10.1515/acph-2015-0013 |
| work_keys_str_mv | AT zelbieneegle invitropermeationstudiesofphenolicsfromhorsechestnutseedgelspreparedwithdifferentpolyacrylicacidpolymerderivatives AT draksienegailute invitropermeationstudiesofphenolicsfromhorsechestnutseedgelspreparedwithdifferentpolyacrylicacidpolymerderivatives AT savickasarunas invitropermeationstudiesofphenolicsfromhorsechestnutseedgelspreparedwithdifferentpolyacrylicacidpolymerderivatives AT kopustinskienedalia invitropermeationstudiesofphenolicsfromhorsechestnutseedgelspreparedwithdifferentpolyacrylicacidpolymerderivatives AT masteikovaruta invitropermeationstudiesofphenolicsfromhorsechestnutseedgelspreparedwithdifferentpolyacrylicacidpolymerderivatives AT bernatonienejurga invitropermeationstudiesofphenolicsfromhorsechestnutseedgelspreparedwithdifferentpolyacrylicacidpolymerderivatives |