Corneal Sublayers Thickness Estimation Obtained by High-Resolution FD-OCT
This paper presents a novel processing technique which can be applied to corneal in vivo images obtained with optical coherence tomograms across the central meridian of the cornea. The method allows to estimate the thickness of the corneal sublayers (Epithelium, Bowman’s layer, Stroma, Endothelium,...
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | International Journal of Biomedical Imaging |
| Online Access: | http://dx.doi.org/10.1155/2013/989624 |
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| _version_ | 1849690390934847488 |
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| author | Diego Alberto Roberto Garello |
| author_facet | Diego Alberto Roberto Garello |
| author_sort | Diego Alberto |
| collection | DOAJ |
| description | This paper presents a novel processing technique which can be applied to corneal in vivo images obtained with optical coherence tomograms across the central meridian of the cornea. The method allows to estimate the thickness of the corneal sublayers (Epithelium, Bowman’s layer, Stroma, Endothelium, and whole corneal thickness) at any location, including the center and the midperiphery, on both nasal and temporal sides. The analysis is carried out on both the pixel and subpixel scales to reduce the uncertainty in thickness estimations. This technique allows quick and noninvasive assessment of patients. As an example of application and validation, we present the results obtained from the analysis of 52 healthy subjects, each with 3 scans per eye, for a total of more than 300 images. Particular attention has been paid to the statistical interpretation of the obtained results to find a representative assessment of each sublayer’s thickness. |
| format | Article |
| id | doaj-art-efbb0852ef3745ffae7df757530da532 |
| institution | DOAJ |
| issn | 1687-4188 1687-4196 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Biomedical Imaging |
| spelling | doaj-art-efbb0852ef3745ffae7df757530da5322025-08-20T03:21:19ZengWileyInternational Journal of Biomedical Imaging1687-41881687-41962013-01-01201310.1155/2013/989624989624Corneal Sublayers Thickness Estimation Obtained by High-Resolution FD-OCTDiego Alberto0Roberto Garello1Department of Electronics and Telecommunications, Politecnico di Torino, Corso Duca Degli Abruzzi 24, 10129 Turin, ItalyDepartment of Electronics and Telecommunications, Politecnico di Torino, Corso Duca Degli Abruzzi 24, 10129 Turin, ItalyThis paper presents a novel processing technique which can be applied to corneal in vivo images obtained with optical coherence tomograms across the central meridian of the cornea. The method allows to estimate the thickness of the corneal sublayers (Epithelium, Bowman’s layer, Stroma, Endothelium, and whole corneal thickness) at any location, including the center and the midperiphery, on both nasal and temporal sides. The analysis is carried out on both the pixel and subpixel scales to reduce the uncertainty in thickness estimations. This technique allows quick and noninvasive assessment of patients. As an example of application and validation, we present the results obtained from the analysis of 52 healthy subjects, each with 3 scans per eye, for a total of more than 300 images. Particular attention has been paid to the statistical interpretation of the obtained results to find a representative assessment of each sublayer’s thickness.http://dx.doi.org/10.1155/2013/989624 |
| spellingShingle | Diego Alberto Roberto Garello Corneal Sublayers Thickness Estimation Obtained by High-Resolution FD-OCT International Journal of Biomedical Imaging |
| title | Corneal Sublayers Thickness Estimation Obtained by High-Resolution FD-OCT |
| title_full | Corneal Sublayers Thickness Estimation Obtained by High-Resolution FD-OCT |
| title_fullStr | Corneal Sublayers Thickness Estimation Obtained by High-Resolution FD-OCT |
| title_full_unstemmed | Corneal Sublayers Thickness Estimation Obtained by High-Resolution FD-OCT |
| title_short | Corneal Sublayers Thickness Estimation Obtained by High-Resolution FD-OCT |
| title_sort | corneal sublayers thickness estimation obtained by high resolution fd oct |
| url | http://dx.doi.org/10.1155/2013/989624 |
| work_keys_str_mv | AT diegoalberto cornealsublayersthicknessestimationobtainedbyhighresolutionfdoct AT robertogarello cornealsublayersthicknessestimationobtainedbyhighresolutionfdoct |