Staphylococcus aureus thermonuclease NucA is a key virulence factor in septic arthritis
Abstract Septic arthritis, primarily caused by Staphylococcus aureus, poses a significant risk of both mortality and morbidity due to its aggressive nature. The nuc1-encoded thermonuclease NucA of S. aureus degrades extracellular DNA/RNA, allowing the pathogen to escape neutrophil extracellular trap...
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| Main Authors: | Ningna Li, Meghshree Vinod Deshmukh, Filiz Sahin, Nourhane Hafza, Aparna Viswanathan Ammanath, Sabrina Ehnert, Andreas Nüssler, Alexander N. R. Weber, Tao Jin, Friedrich Götz |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-04-01
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| Series: | Communications Biology |
| Online Access: | https://doi.org/10.1038/s42003-025-07920-4 |
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