Implications of anesthetic techniques on patients' recovery in laparoscopic cholecystectomy

Background/Aim. Different techniques of general anesthesia are used for laparoscopic cholecystectomy (LC). The aim of the study was to establish the best anesthetic technique for achieving better results during awakening affecting not only patient's recovery, but activities of anesthesiological...

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Main Authors: Stošić Biljana, Stojanović Miroslav, Janković Radmilo, Radojković Milan, Ignjatović Nebojša
Format: Article
Language:English
Published: Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade 2009-01-01
Series:Vojnosanitetski Pregled
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Online Access:http://www.doiserbia.nb.rs/img/doi/0042-8450/2009/0042-84500906421S.pdf
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author Stošić Biljana
Stojanović Miroslav
Janković Radmilo
Radojković Milan
Ignjatović Nebojša
author_facet Stošić Biljana
Stojanović Miroslav
Janković Radmilo
Radojković Milan
Ignjatović Nebojša
author_sort Stošić Biljana
collection DOAJ
description Background/Aim. Different techniques of general anesthesia are used for laparoscopic cholecystectomy (LC). The aim of the study was to establish the best anesthetic technique for achieving better results during awakening affecting not only patient's recovery, but activities of anesthesiological team, as well. Methods. The study was conducted as a prospective comparative clinical trial. The patients (n=90) were classified according to the applied anesthetic technique into two groups: Volatile Induction and Maintenance Anesthesia (VIMA) with sevofluran and Target Controlled Infusion (TCI). The results relating to parameters of recovery after anesthesia and surgery were compared between these two groups. The following parameters were analyzed: demographic patients' characteristics, duration of anesthesia, the times to eye opening, to respond to a command, to extubation, and to orientation, from the last anesthetic dose receiving until post anesthesia discharge (PAD), frequency of postoperative nausea, vomiting and agitation (PONVA). Results. In the examined groups there were no statistically significant differences in the duration of anesthesia (68.29 ± 6.47 vs 66.29 ± 11.97 min, p = 0.327). The time to eye opening was significantly shorter in the group VIMA compared to the group TCI (4.49 ± 1.20 vs 7.42 ± 1.25 min, p = 0.000), as well as the time to respond to a command (5.93 ± 1.12 vs 8.47 ± 1.08 min, p = 0.000). The patients anesthetized with VIMA technique were statistically significantly extubated earlier (6.84 ± 1.19 vs 9.69 ± 1.31 min, p = 0.000). Considering orientation time, there was also statistically significant difference between the two groups (7.51 ± 0.97 vs 11.60 ± 1.75 min, p = 0.000). There was no statistically significant difference in PAD time duration (19.42 ± 5.99 vs 20.80 ± 1.59 min, p = 0.142). There were no statistically significant differences in PONVA events between the examined groups. Conclusion. This study showed that VIMA technique with sevofluran in LC provides faster and more qualitative recovery of patients. Thus this technique should be applied in everyday anesthesiological procedures in LC, as well as in other minimally invasive videoendoscopic surgical procedures.
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spelling doaj-art-ef9bf465ca784f8aadeea799c227e7dd2025-08-20T02:22:05ZengMinistry of Defence of the Republic of Serbia, University of Defence, BelgradeVojnosanitetski Pregled0042-84502009-01-0166642142610.2298/VSP0906421SImplications of anesthetic techniques on patients' recovery in laparoscopic cholecystectomyStošić BiljanaStojanović MiroslavJanković RadmiloRadojković MilanIgnjatović NebojšaBackground/Aim. Different techniques of general anesthesia are used for laparoscopic cholecystectomy (LC). The aim of the study was to establish the best anesthetic technique for achieving better results during awakening affecting not only patient's recovery, but activities of anesthesiological team, as well. Methods. The study was conducted as a prospective comparative clinical trial. The patients (n=90) were classified according to the applied anesthetic technique into two groups: Volatile Induction and Maintenance Anesthesia (VIMA) with sevofluran and Target Controlled Infusion (TCI). The results relating to parameters of recovery after anesthesia and surgery were compared between these two groups. The following parameters were analyzed: demographic patients' characteristics, duration of anesthesia, the times to eye opening, to respond to a command, to extubation, and to orientation, from the last anesthetic dose receiving until post anesthesia discharge (PAD), frequency of postoperative nausea, vomiting and agitation (PONVA). Results. In the examined groups there were no statistically significant differences in the duration of anesthesia (68.29 ± 6.47 vs 66.29 ± 11.97 min, p = 0.327). The time to eye opening was significantly shorter in the group VIMA compared to the group TCI (4.49 ± 1.20 vs 7.42 ± 1.25 min, p = 0.000), as well as the time to respond to a command (5.93 ± 1.12 vs 8.47 ± 1.08 min, p = 0.000). The patients anesthetized with VIMA technique were statistically significantly extubated earlier (6.84 ± 1.19 vs 9.69 ± 1.31 min, p = 0.000). Considering orientation time, there was also statistically significant difference between the two groups (7.51 ± 0.97 vs 11.60 ± 1.75 min, p = 0.000). There was no statistically significant difference in PAD time duration (19.42 ± 5.99 vs 20.80 ± 1.59 min, p = 0.142). There were no statistically significant differences in PONVA events between the examined groups. Conclusion. This study showed that VIMA technique with sevofluran in LC provides faster and more qualitative recovery of patients. Thus this technique should be applied in everyday anesthesiological procedures in LC, as well as in other minimally invasive videoendoscopic surgical procedures.http://www.doiserbia.nb.rs/img/doi/0042-8450/2009/0042-84500906421S.pdfanesthesia, inhalationanesthesia, intravenousanesthesia recovery periodcholecystectomy, laparoscopicpostoperative period
spellingShingle Stošić Biljana
Stojanović Miroslav
Janković Radmilo
Radojković Milan
Ignjatović Nebojša
Implications of anesthetic techniques on patients' recovery in laparoscopic cholecystectomy
Vojnosanitetski Pregled
anesthesia, inhalation
anesthesia, intravenous
anesthesia recovery period
cholecystectomy, laparoscopic
postoperative period
title Implications of anesthetic techniques on patients' recovery in laparoscopic cholecystectomy
title_full Implications of anesthetic techniques on patients' recovery in laparoscopic cholecystectomy
title_fullStr Implications of anesthetic techniques on patients' recovery in laparoscopic cholecystectomy
title_full_unstemmed Implications of anesthetic techniques on patients' recovery in laparoscopic cholecystectomy
title_short Implications of anesthetic techniques on patients' recovery in laparoscopic cholecystectomy
title_sort implications of anesthetic techniques on patients recovery in laparoscopic cholecystectomy
topic anesthesia, inhalation
anesthesia, intravenous
anesthesia recovery period
cholecystectomy, laparoscopic
postoperative period
url http://www.doiserbia.nb.rs/img/doi/0042-8450/2009/0042-84500906421S.pdf
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