Application of hydroxychloroquine for IgA nephropathy

Globally IgA nephropathy has been the most common glomerular disease.According to the guidelines of Kidney Disease: Improving Global Outcomes(KDIGO)for treating IgA nephropathy, renin-angiotensin-aldosterone system inhibitors(RAASi)may effectively alleviate proteinuria and control blood pressure, th...

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Main Authors: Xiao Yong-zhen, Yang Xiao
Format: Article
Language:zho
Published: Editorial Department of Journal of Clinical Nephrology 2021-01-01
Series:Linchuang shenzangbing zazhi
Subjects:
Online Access:http://www.lcszb.com/thesisDetails?columnId=57904128&Fpath=home&index=0
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author Xiao Yong-zhen
Yang Xiao
author_facet Xiao Yong-zhen
Yang Xiao
author_sort Xiao Yong-zhen
collection DOAJ
description Globally IgA nephropathy has been the most common glomerular disease.According to the guidelines of Kidney Disease: Improving Global Outcomes(KDIGO)for treating IgA nephropathy, renin-angiotensin-aldosterone system inhibitors(RAASi)may effectively alleviate proteinuria and control blood pressure, thereby significantly delaying the progression of the disease.Glucocorticoids or immunosuppressants are routinely applied.Hydroxychloroquine(HCQ)is an immunomodulatory agent for malaria and autoimmune diseases.Recent studies have demonstrated that HCQ was efficacious for persistent proteinuria in patients with IgA nephropathy.The relevant literature reports were retrieved for comprehensively reviewing the application characteristics of HCQ for IgA nephropathy.
format Article
id doaj-art-ef986d6cb6794c25beeac4f027babc23
institution OA Journals
issn 1671-2390
language zho
publishDate 2021-01-01
publisher Editorial Department of Journal of Clinical Nephrology
record_format Article
series Linchuang shenzangbing zazhi
spelling doaj-art-ef986d6cb6794c25beeac4f027babc232025-08-20T02:16:10ZzhoEditorial Department of Journal of Clinical NephrologyLinchuang shenzangbing zazhi1671-23902021-01-0125325757904128Application of hydroxychloroquine for IgA nephropathyXiao Yong-zhenYang XiaoGlobally IgA nephropathy has been the most common glomerular disease.According to the guidelines of Kidney Disease: Improving Global Outcomes(KDIGO)for treating IgA nephropathy, renin-angiotensin-aldosterone system inhibitors(RAASi)may effectively alleviate proteinuria and control blood pressure, thereby significantly delaying the progression of the disease.Glucocorticoids or immunosuppressants are routinely applied.Hydroxychloroquine(HCQ)is an immunomodulatory agent for malaria and autoimmune diseases.Recent studies have demonstrated that HCQ was efficacious for persistent proteinuria in patients with IgA nephropathy.The relevant literature reports were retrieved for comprehensively reviewing the application characteristics of HCQ for IgA nephropathy.http://www.lcszb.com/thesisDetails?columnId=57904128&Fpath=home&index=0HydroxychloroquineIgA nephropathyImmunityProteinuria
spellingShingle Xiao Yong-zhen
Yang Xiao
Application of hydroxychloroquine for IgA nephropathy
Linchuang shenzangbing zazhi
Hydroxychloroquine
IgA nephropathy
Immunity
Proteinuria
title Application of hydroxychloroquine for IgA nephropathy
title_full Application of hydroxychloroquine for IgA nephropathy
title_fullStr Application of hydroxychloroquine for IgA nephropathy
title_full_unstemmed Application of hydroxychloroquine for IgA nephropathy
title_short Application of hydroxychloroquine for IgA nephropathy
title_sort application of hydroxychloroquine for iga nephropathy
topic Hydroxychloroquine
IgA nephropathy
Immunity
Proteinuria
url http://www.lcszb.com/thesisDetails?columnId=57904128&Fpath=home&index=0
work_keys_str_mv AT xiaoyongzhen applicationofhydroxychloroquineforiganephropathy
AT yangxiao applicationofhydroxychloroquineforiganephropathy