Targeting 160 candidate genes for blood pressure regulation with a genome-wide genotyping array.

Targeting 160 candidate genes for blood pressure regulation with a genome-wide genotyping array.

The outcome of Genome-Wide Association Studies (GWAS) has challenged the field of blood pressure (BP) genetics as previous candidate genes have not been among the top loci in these scans. We used Affymetrix 500K genotyping data of KORA S3 cohort (n = 1,644; Southern-Germany) to address (i) SNP cover...

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Main Authors: Siim Sõber, Elin Org, Katrin Kepp, Peeter Juhanson, Susana Eyheramendy, Christian Gieger, Peter Lichtner, Norman Klopp, Gudrun Veldre, Margus Viigimaa, Angela Döring, Kooperative Gesundheitsforschung in der Region Augsburg Study, Margus Putku, Piret Kelgo, HYPertension in ESTonia Study, Sue Shaw-Hawkins, Philip Howard, Abiodun Onipinla, Richard J Dobson, Stephen J Newhouse, Morris Brown, Anna Dominiczak, John Connell, Nilesh Samani, Martin Farrall, MRC British Genetics of Hypertension Study, Mark J Caulfield, Patricia B Munroe, Thomas Illig, H-Erich Wichmann, Thomas Meitinger, Maris Laan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-06-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0006034&type=printable
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