Hsa-miR-146b-3p promotes endothelial cell dysfunction and atherosclerosis development by targeting CREB3L3 to regulate the PI3K/Akt signaling pathway

Hsa-miR-146b-3p promotes endothelial cell dysfunction and atherosclerosis development by targeting CREB3L3 to regulate the PI3K/Akt signaling pathway

Objective To explore the effects of hsa-miR-146b-3p on endothelial cells and the possible roles and mechanisms of hsa-miR-146b-3p in the development of atherosclerosis. Methods Lentivirus was used to construct an endothelial cell intervention model in EA. hy926 cells. The cells were categorized into...

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Bibliographic Details
Main Authors: Shifan ZHOU, Shuming ZHANG, Ningyuan CHEN, Ling HUANG, Chongyang SONG, Shangling PAN, Junhua PENG
Format: Article
Language:zho
Published: Editorial Office of Journal of Guangxi Medical University 2025-06-01
Series:Guangxi Yike Daxue xuebao
Subjects:
hsa-mir-146b-3p
coronary heart disease
rna sequencing
pi3k/akt signaling pathway
Online Access:https://journal.gxmu.edu.cn/article/doi/10.16190/j.cnki.45-1211/r.2025.03.003
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