Steroid-Responsive Encephalopathy Associated with Autoimmune Thyroiditis Presenting as Confusion, Dysphasia, and Myoclonus

Steroid response encephalopathy associated with autoimmune thyroiditis (SREAT), or Hashimoto’s encephalopathy, is a rare disorder believed to be immune-mediated. It is most often characterized by a subacute onset of confusion with altered level of consciousness, seizures, and myoclonus. We describe...

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Main Authors: S. A. Ryan, C. Kennedy, H. J. Harrington
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Case Reports in Medicine
Online Access:http://dx.doi.org/10.1155/2012/782127
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author S. A. Ryan
C. Kennedy
H. J. Harrington
author_facet S. A. Ryan
C. Kennedy
H. J. Harrington
author_sort S. A. Ryan
collection DOAJ
description Steroid response encephalopathy associated with autoimmune thyroiditis (SREAT), or Hashimoto’s encephalopathy, is a rare disorder believed to be immune-mediated. It is most often characterized by a subacute onset of confusion with altered level of consciousness, seizures, and myoclonus. We describe the case of a 48-year-old gentleman who presented with confusion and dysphasia. Specific clinical features and laboratory results led to a diagnosis of Hashimoto’s encephalopathy. This case highlights the core features of this condition and the potential for complete response to steroid therapy.
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spelling doaj-art-ef8eba89a59042759c7beb2b99b0a08e2025-08-20T03:21:13ZengWileyCase Reports in Medicine1687-96271687-96352012-01-01201210.1155/2012/782127782127Steroid-Responsive Encephalopathy Associated with Autoimmune Thyroiditis Presenting as Confusion, Dysphasia, and MyoclonusS. A. Ryan0C. Kennedy1H. J. Harrington2Department of Neurology, Mercy University Hospital, Cork, IrelandDepartment of Neurology, Mercy University Hospital, Cork, IrelandDepartment of Neurology, Mercy University Hospital, Cork, IrelandSteroid response encephalopathy associated with autoimmune thyroiditis (SREAT), or Hashimoto’s encephalopathy, is a rare disorder believed to be immune-mediated. It is most often characterized by a subacute onset of confusion with altered level of consciousness, seizures, and myoclonus. We describe the case of a 48-year-old gentleman who presented with confusion and dysphasia. Specific clinical features and laboratory results led to a diagnosis of Hashimoto’s encephalopathy. This case highlights the core features of this condition and the potential for complete response to steroid therapy.http://dx.doi.org/10.1155/2012/782127
spellingShingle S. A. Ryan
C. Kennedy
H. J. Harrington
Steroid-Responsive Encephalopathy Associated with Autoimmune Thyroiditis Presenting as Confusion, Dysphasia, and Myoclonus
Case Reports in Medicine
title Steroid-Responsive Encephalopathy Associated with Autoimmune Thyroiditis Presenting as Confusion, Dysphasia, and Myoclonus
title_full Steroid-Responsive Encephalopathy Associated with Autoimmune Thyroiditis Presenting as Confusion, Dysphasia, and Myoclonus
title_fullStr Steroid-Responsive Encephalopathy Associated with Autoimmune Thyroiditis Presenting as Confusion, Dysphasia, and Myoclonus
title_full_unstemmed Steroid-Responsive Encephalopathy Associated with Autoimmune Thyroiditis Presenting as Confusion, Dysphasia, and Myoclonus
title_short Steroid-Responsive Encephalopathy Associated with Autoimmune Thyroiditis Presenting as Confusion, Dysphasia, and Myoclonus
title_sort steroid responsive encephalopathy associated with autoimmune thyroiditis presenting as confusion dysphasia and myoclonus
url http://dx.doi.org/10.1155/2012/782127
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AT hjharrington steroidresponsiveencephalopathyassociatedwithautoimmunethyroiditispresentingasconfusiondysphasiaandmyoclonus