Pan‐cancer analysis shapes the understanding of cancer biology and medicine

Abstract Advances in multi‐omics datasets and analytical methods have revolutionized cancer research, offering a comprehensive, pan‐cancer perspective. Pan‐cancer studies identify shared mechanisms and unique traits across different cancer types, which are reshaping diagnostic and treatment strategi...

Full description

Saved in:
Bibliographic Details
Main Authors: Xiaoping Cen, Yuanyuan Lan, Jiansheng Zou, Ruilin Chen, Can Hu, Yahan Tong, Chen Zhang, Jingyue Chen, Yuanmei Wang, Run Zhou, Weiwei He, Tianyu Lu, Fred Dubee, Dragomirka Jovic, Wei Dong, Qingqing Gao, Man Ma, Youyong Lu, Yu Xue, Xiangdong Cheng, Yixue Li, Huanming Yang
Format: Article
Language:English
Published: Wiley 2025-07-01
Series:Cancer Communications
Subjects:
Online Access:https://doi.org/10.1002/cac2.70008
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1849243634583470080
author Xiaoping Cen
Yuanyuan Lan
Jiansheng Zou
Ruilin Chen
Can Hu
Yahan Tong
Chen Zhang
Jingyue Chen
Yuanmei Wang
Run Zhou
Weiwei He
Tianyu Lu
Fred Dubee
Dragomirka Jovic
Wei Dong
Qingqing Gao
Man Ma
Youyong Lu
Yu Xue
Xiangdong Cheng
Yixue Li
Huanming Yang
author_facet Xiaoping Cen
Yuanyuan Lan
Jiansheng Zou
Ruilin Chen
Can Hu
Yahan Tong
Chen Zhang
Jingyue Chen
Yuanmei Wang
Run Zhou
Weiwei He
Tianyu Lu
Fred Dubee
Dragomirka Jovic
Wei Dong
Qingqing Gao
Man Ma
Youyong Lu
Yu Xue
Xiangdong Cheng
Yixue Li
Huanming Yang
author_sort Xiaoping Cen
collection DOAJ
description Abstract Advances in multi‐omics datasets and analytical methods have revolutionized cancer research, offering a comprehensive, pan‐cancer perspective. Pan‐cancer studies identify shared mechanisms and unique traits across different cancer types, which are reshaping diagnostic and treatment strategies. However, continued innovation is required to refine these approaches and deepen our understanding of cancer biology and medicine. This review summarized key findings from pan‐cancer research and  explored their potential to drive future advancements in oncology.
format Article
id doaj-art-ef8b1ffd8954468fbc99a6b88e8cc3f6
institution Kabale University
issn 2523-3548
language English
publishDate 2025-07-01
publisher Wiley
record_format Article
series Cancer Communications
spelling doaj-art-ef8b1ffd8954468fbc99a6b88e8cc3f62025-08-20T03:59:25ZengWileyCancer Communications2523-35482025-07-0145772874610.1002/cac2.70008Pan‐cancer analysis shapes the understanding of cancer biology and medicineXiaoping Cen0Yuanyuan Lan1Jiansheng Zou2Ruilin Chen3Can Hu4Yahan Tong5Chen Zhang6Jingyue Chen7Yuanmei Wang8Run Zhou9Weiwei He10Tianyu Lu11Fred Dubee12Dragomirka Jovic13Wei Dong14Qingqing Gao15Man Ma16Youyong Lu17Yu Xue18Xiangdong Cheng19Yixue Li20Huanming Yang21College of Life Sciences, University of Chinese Academy of Sciences Beijing P. R. ChinaCollege of Life Sciences, University of Chinese Academy of Sciences Beijing P. R. ChinaHIM‐BGI Omics Center, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences (CAS) Hangzhou Zhejiang P. R. ChinaHIM‐BGI Omics Center, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences (CAS) Hangzhou Zhejiang P. R. ChinaZhejiang Cancer Hospital, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences Hangzhou Zhejiang P. R. ChinaZhejiang Cancer Hospital, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences Hangzhou Zhejiang P. R. ChinaCollege of Life Sciences, University of Chinese Academy of Sciences Beijing P. R. ChinaHIM‐BGI Omics Center, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences (CAS) Hangzhou Zhejiang P. R. ChinaCollege of Life Sciences, University of Chinese Academy of Sciences Beijing P. R. ChinaCollege of Life Sciences, University of Chinese Academy of Sciences Beijing P. R. ChinaCollege of Life Sciences, University of Chinese Academy of Sciences Beijing P. R. ChinaCollege of Life Sciences, University of Chinese Academy of Sciences Beijing P. R. ChinaBGI Research Shenzhen Guangdong P. R. ChinaBGI Research Shenzhen Guangdong P. R. ChinaHIM‐BGI Omics Center, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences (CAS) Hangzhou Zhejiang P. R. ChinaCollege of Life Sciences, University of Chinese Academy of Sciences Beijing P. R. ChinaHIM‐BGI Omics Center, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences (CAS) Hangzhou Zhejiang P. R. ChinaLaboratory of Molecular Oncology, Peking University Cancer Hospital and Institute Beijing P. R. ChinaMOE Key Laboratory of Molecular Biophysics, Hubei Bioinformatics and Molecular Imaging Key Laboratory, Center for Artificial Intelligence Biology, College of Life Science and Technology, Huazhong University of Science and Technology Wuhan Hubei P. R. ChinaZhejiang Cancer Hospital, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences Hangzhou Zhejiang P. R. ChinaGuangzhou National Laboratory Guangzhou Guangdong P. R. ChinaCollege of Life Sciences, University of Chinese Academy of Sciences Beijing P. R. ChinaAbstract Advances in multi‐omics datasets and analytical methods have revolutionized cancer research, offering a comprehensive, pan‐cancer perspective. Pan‐cancer studies identify shared mechanisms and unique traits across different cancer types, which are reshaping diagnostic and treatment strategies. However, continued innovation is required to refine these approaches and deepen our understanding of cancer biology and medicine. This review summarized key findings from pan‐cancer research and  explored their potential to drive future advancements in oncology.https://doi.org/10.1002/cac2.70008artificial intelligencecancer biologycancer treatmentmulti‐omicspan‐cancer
spellingShingle Xiaoping Cen
Yuanyuan Lan
Jiansheng Zou
Ruilin Chen
Can Hu
Yahan Tong
Chen Zhang
Jingyue Chen
Yuanmei Wang
Run Zhou
Weiwei He
Tianyu Lu
Fred Dubee
Dragomirka Jovic
Wei Dong
Qingqing Gao
Man Ma
Youyong Lu
Yu Xue
Xiangdong Cheng
Yixue Li
Huanming Yang
Pan‐cancer analysis shapes the understanding of cancer biology and medicine
Cancer Communications
artificial intelligence
cancer biology
cancer treatment
multi‐omics
pan‐cancer
title Pan‐cancer analysis shapes the understanding of cancer biology and medicine
title_full Pan‐cancer analysis shapes the understanding of cancer biology and medicine
title_fullStr Pan‐cancer analysis shapes the understanding of cancer biology and medicine
title_full_unstemmed Pan‐cancer analysis shapes the understanding of cancer biology and medicine
title_short Pan‐cancer analysis shapes the understanding of cancer biology and medicine
title_sort pan cancer analysis shapes the understanding of cancer biology and medicine
topic artificial intelligence
cancer biology
cancer treatment
multi‐omics
pan‐cancer
url https://doi.org/10.1002/cac2.70008
work_keys_str_mv AT xiaopingcen pancanceranalysisshapestheunderstandingofcancerbiologyandmedicine
AT yuanyuanlan pancanceranalysisshapestheunderstandingofcancerbiologyandmedicine
AT jianshengzou pancanceranalysisshapestheunderstandingofcancerbiologyandmedicine
AT ruilinchen pancanceranalysisshapestheunderstandingofcancerbiologyandmedicine
AT canhu pancanceranalysisshapestheunderstandingofcancerbiologyandmedicine
AT yahantong pancanceranalysisshapestheunderstandingofcancerbiologyandmedicine
AT chenzhang pancanceranalysisshapestheunderstandingofcancerbiologyandmedicine
AT jingyuechen pancanceranalysisshapestheunderstandingofcancerbiologyandmedicine
AT yuanmeiwang pancanceranalysisshapestheunderstandingofcancerbiologyandmedicine
AT runzhou pancanceranalysisshapestheunderstandingofcancerbiologyandmedicine
AT weiweihe pancanceranalysisshapestheunderstandingofcancerbiologyandmedicine
AT tianyulu pancanceranalysisshapestheunderstandingofcancerbiologyandmedicine
AT freddubee pancanceranalysisshapestheunderstandingofcancerbiologyandmedicine
AT dragomirkajovic pancanceranalysisshapestheunderstandingofcancerbiologyandmedicine
AT weidong pancanceranalysisshapestheunderstandingofcancerbiologyandmedicine
AT qingqinggao pancanceranalysisshapestheunderstandingofcancerbiologyandmedicine
AT manma pancanceranalysisshapestheunderstandingofcancerbiologyandmedicine
AT youyonglu pancanceranalysisshapestheunderstandingofcancerbiologyandmedicine
AT yuxue pancanceranalysisshapestheunderstandingofcancerbiologyandmedicine
AT xiangdongcheng pancanceranalysisshapestheunderstandingofcancerbiologyandmedicine
AT yixueli pancanceranalysisshapestheunderstandingofcancerbiologyandmedicine
AT huanmingyang pancanceranalysisshapestheunderstandingofcancerbiologyandmedicine