The predictive value of preprocedural laboratory data in patients with coronary artery restenosis in various types of stents
Aim. To identify the effect of preprocedural laboratory parameters on the occurrence of in-stent restenosis in various types of stents, to assess the significance of gender, age and various forms of coronary artery disease (CAD) as risk factors for coronary artery restenosis after stenting.Material...
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«FIRMA «SILICEA» LLC
2019-04-01
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| Series: | Российский кардиологический журнал |
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| Online Access: | https://russjcardiol.elpub.ru/jour/article/view/3176 |
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| author | D. V. Shames A. S. Galyavich Z. M. Galeeva L. V. Baleeva |
| author_facet | D. V. Shames A. S. Galyavich Z. M. Galeeva L. V. Baleeva |
| author_sort | D. V. Shames |
| collection | DOAJ |
| description | Aim. To identify the effect of preprocedural laboratory parameters on the occurrence of in-stent restenosis in various types of stents, to assess the significance of gender, age and various forms of coronary artery disease (CAD) as risk factors for coronary artery restenosis after stenting.Material and methods. The study included 436 patients with CAD, which were divided into 2 groups. The study group included 218 patients with in-stent restenosis. The control group consisted of 218 patients with CAD without in-stent restenosis. Inclusion criteria were acute or chronic form of CAD, age 45-74 years, CAG and percutaneous coronary intervention (PCI) with emergency or planned stenting of the native coronary artery, repeated CAG in history due to signs/symptoms of myocardial ischemia. Exclusion criteria: age younger than 45 years and over 74 years, coronary artery bypass surgery (CABG), cancer, autoimmune disease, anemia, liver failure, chronic kidney disease S4-S5, recent blood transfusion, hypo-or hyperthyroidism.Results. According to the study, the risk in-stent restenosis is 5,2 times higher in patients in the 65-69 years age group and 9,9 times higher in the 70-74 years age group compared with the group of young patients (45-49 years). In-stent restenosis is 2,7 times more common in men than in women. Predictors of restenosis were red cell distribution width, mean platelet volume, Gensini score with OR 1,5; 1,4; 1,1; 1,5, respectively.Conclusion. Risk factors for coronary artery restenosis after stenting are markers of chronic inflammation, such as the red cell distribution width, mean platelet volume. The risk of restenosis is higher in the male population. In old age, the risk of restenosis increases, however, young people and middle-aged people do not differ in risk of in-stent restenosis. |
| format | Article |
| id | doaj-art-ef8552ef41ed4ec5baf4f4e42245e155 |
| institution | DOAJ |
| issn | 1560-4071 2618-7620 |
| language | Russian |
| publishDate | 2019-04-01 |
| publisher | «FIRMA «SILICEA» LLC |
| record_format | Article |
| series | Российский кардиологический журнал |
| spelling | doaj-art-ef8552ef41ed4ec5baf4f4e42245e1552025-08-20T03:21:26Zrus«FIRMA «SILICEA» LLCРоссийский кардиологический журнал1560-40712618-76202019-04-0103545910.15829/1560-4071-2019-3-54-592595The predictive value of preprocedural laboratory data in patients with coronary artery restenosis in various types of stentsD. V. Shames0A. S. Galyavich1Z. M. Galeeva2L. V. Baleeva3Kazan State Medical UniversityKazan State Medical UniversityKazan State Medical UniversityKazan State Medical UniversityAim. To identify the effect of preprocedural laboratory parameters on the occurrence of in-stent restenosis in various types of stents, to assess the significance of gender, age and various forms of coronary artery disease (CAD) as risk factors for coronary artery restenosis after stenting.Material and methods. The study included 436 patients with CAD, which were divided into 2 groups. The study group included 218 patients with in-stent restenosis. The control group consisted of 218 patients with CAD without in-stent restenosis. Inclusion criteria were acute or chronic form of CAD, age 45-74 years, CAG and percutaneous coronary intervention (PCI) with emergency or planned stenting of the native coronary artery, repeated CAG in history due to signs/symptoms of myocardial ischemia. Exclusion criteria: age younger than 45 years and over 74 years, coronary artery bypass surgery (CABG), cancer, autoimmune disease, anemia, liver failure, chronic kidney disease S4-S5, recent blood transfusion, hypo-or hyperthyroidism.Results. According to the study, the risk in-stent restenosis is 5,2 times higher in patients in the 65-69 years age group and 9,9 times higher in the 70-74 years age group compared with the group of young patients (45-49 years). In-stent restenosis is 2,7 times more common in men than in women. Predictors of restenosis were red cell distribution width, mean platelet volume, Gensini score with OR 1,5; 1,4; 1,1; 1,5, respectively.Conclusion. Risk factors for coronary artery restenosis after stenting are markers of chronic inflammation, such as the red cell distribution width, mean platelet volume. The risk of restenosis is higher in the male population. In old age, the risk of restenosis increases, however, young people and middle-aged people do not differ in risk of in-stent restenosis.https://russjcardiol.elpub.ru/jour/article/view/3176restenosiscoronary artery diseasepercutaneous coronary interventionholometallic stentdrug-eluting stentpredictors |
| spellingShingle | D. V. Shames A. S. Galyavich Z. M. Galeeva L. V. Baleeva The predictive value of preprocedural laboratory data in patients with coronary artery restenosis in various types of stents Российский кардиологический журнал restenosis coronary artery disease percutaneous coronary intervention holometallic stent drug-eluting stent predictors |
| title | The predictive value of preprocedural laboratory data in patients with coronary artery restenosis in various types of stents |
| title_full | The predictive value of preprocedural laboratory data in patients with coronary artery restenosis in various types of stents |
| title_fullStr | The predictive value of preprocedural laboratory data in patients with coronary artery restenosis in various types of stents |
| title_full_unstemmed | The predictive value of preprocedural laboratory data in patients with coronary artery restenosis in various types of stents |
| title_short | The predictive value of preprocedural laboratory data in patients with coronary artery restenosis in various types of stents |
| title_sort | predictive value of preprocedural laboratory data in patients with coronary artery restenosis in various types of stents |
| topic | restenosis coronary artery disease percutaneous coronary intervention holometallic stent drug-eluting stent predictors |
| url | https://russjcardiol.elpub.ru/jour/article/view/3176 |
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