Development of an iPSC-derived immunocompetent skin model for identification of skin sensitizing substances
The development of immunocompetent skin models marks a significant advancement in in vitro methods for detecting skin sensitizers while adhering to the 3R principles, which aim to reduce, refine, and replace animal testing. This study introduces for the first time an advanced immunocompetent skin mo...
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| Main Authors: | Marla Dubau, Tarada Tripetchr, Lava Mahmoud, Fabian Schumacher, Burkhard Kleuser |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2025-05-01
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| Series: | Journal of Tissue Engineering |
| Online Access: | https://doi.org/10.1177/20417314251336296 |
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