Stereotactic Body Radiotherapy for Metachronous Multisite Oligo-Recurrence: A Long-Surviving Case with Sequential Oligo-Recurrence in Four Different Organs Treated Using Locally Radical Radiotherapy and a Review of the Literature

Stereotactic body radiotherapy (SBRT) for oligometastases represents a recent trend in radiation oncology. While abundant data are available regarding the use of SBRT for the treatment of lung or liver oligometastases from various retrospective series and prospective trials, relatively little inform...

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Main Authors: Hiroshi Onishi, Masatoki Ozaki, Kengo Kuriyama, Takafumi Komiyama, Kan Marino, Masayuki Araya, Ryo Saito, Shinichi Aoki, Yoshiyasu Maehata, Licht Tominaga, Mitsuhiko Oguri, Iori Watanabe, Kojiro Onohara, Meguru Watanabe, Naoki Sano, Tsutomu Araki
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Pulmonary Medicine
Online Access:http://dx.doi.org/10.1155/2012/713073
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author Hiroshi Onishi
Masatoki Ozaki
Kengo Kuriyama
Takafumi Komiyama
Kan Marino
Masayuki Araya
Ryo Saito
Shinichi Aoki
Yoshiyasu Maehata
Licht Tominaga
Mitsuhiko Oguri
Iori Watanabe
Kojiro Onohara
Meguru Watanabe
Naoki Sano
Tsutomu Araki
author_facet Hiroshi Onishi
Masatoki Ozaki
Kengo Kuriyama
Takafumi Komiyama
Kan Marino
Masayuki Araya
Ryo Saito
Shinichi Aoki
Yoshiyasu Maehata
Licht Tominaga
Mitsuhiko Oguri
Iori Watanabe
Kojiro Onohara
Meguru Watanabe
Naoki Sano
Tsutomu Araki
author_sort Hiroshi Onishi
collection DOAJ
description Stereotactic body radiotherapy (SBRT) for oligometastases represents a recent trend in radiation oncology. While abundant data are available regarding the use of SBRT for the treatment of lung or liver oligometastases from various retrospective series and prospective trials, relatively little information has been accumulated for the treatment of oligometastases at sites other than the lungs and liver, particularly for sequential oligometastases in multiple organs. Oligometastases with primary lesions controlled is called “oligo-recurrence.” We describe herein the case of a lung cancer patient who developed repeated oligo-recurrence at multiple sites that were each controlled by radical radiotherapy and achieved long-term survival and discuss the merits of locally aggressive radiotherapy for this type of disease condition with reviewing the literature. Although further investigation should be undertaken to clarify the benefits, objectives, and methods of SBRT for the treatment of oligometastases, we believe utilization of SBRT may be worthwhile for patients with remote metastases who hope for treatment to acquire better local control and possible longer survival.
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spelling doaj-art-ef80835e1931468ab008a34fcf4988d22025-08-20T03:21:13ZengWileyPulmonary Medicine2090-18362090-18442012-01-01201210.1155/2012/713073713073Stereotactic Body Radiotherapy for Metachronous Multisite Oligo-Recurrence: A Long-Surviving Case with Sequential Oligo-Recurrence in Four Different Organs Treated Using Locally Radical Radiotherapy and a Review of the LiteratureHiroshi Onishi0Masatoki Ozaki1Kengo Kuriyama2Takafumi Komiyama3Kan Marino4Masayuki Araya5Ryo Saito6Shinichi Aoki7Yoshiyasu Maehata8Licht Tominaga9Mitsuhiko Oguri10Iori Watanabe11Kojiro Onohara12Meguru Watanabe13Naoki Sano14Tsutomu Araki15Department of Radiology, School of Medicine, Yamanashi University, 1110 Shimokato, Chuo City, Yamanashi 409-3898, JapanDepartment of Radiology, Shizuoka Municipal Shimizu Hospital, Shizuoka 424-8636, JapanDepartment of Radiology, School of Medicine, Yamanashi University, 1110 Shimokato, Chuo City, Yamanashi 409-3898, JapanDepartment of Radiology, School of Medicine, Yamanashi University, 1110 Shimokato, Chuo City, Yamanashi 409-3898, JapanDepartment of Radiology, School of Medicine, Yamanashi University, 1110 Shimokato, Chuo City, Yamanashi 409-3898, JapanDepartment of Radiology, School of Medicine, Yamanashi University, 1110 Shimokato, Chuo City, Yamanashi 409-3898, JapanDepartment of Radiology, School of Medicine, Yamanashi University, 1110 Shimokato, Chuo City, Yamanashi 409-3898, JapanDepartment of Radiology, School of Medicine, Yamanashi University, 1110 Shimokato, Chuo City, Yamanashi 409-3898, JapanDepartment of Radiology, School of Medicine, Yamanashi University, 1110 Shimokato, Chuo City, Yamanashi 409-3898, JapanDepartment of Radiology, School of Medicine, Yamanashi University, 1110 Shimokato, Chuo City, Yamanashi 409-3898, JapanDepartment of Radiology, School of Medicine, Yamanashi University, 1110 Shimokato, Chuo City, Yamanashi 409-3898, JapanDepartment of Radiology, School of Medicine, Yamanashi University, 1110 Shimokato, Chuo City, Yamanashi 409-3898, JapanDepartment of Radiology, School of Medicine, Yamanashi University, 1110 Shimokato, Chuo City, Yamanashi 409-3898, JapanDepartment of Radiology, School of Medicine, Yamanashi University, 1110 Shimokato, Chuo City, Yamanashi 409-3898, JapanDepartment of Radiology, School of Medicine, Yamanashi University, 1110 Shimokato, Chuo City, Yamanashi 409-3898, JapanDepartment of Radiology, School of Medicine, Yamanashi University, 1110 Shimokato, Chuo City, Yamanashi 409-3898, JapanStereotactic body radiotherapy (SBRT) for oligometastases represents a recent trend in radiation oncology. While abundant data are available regarding the use of SBRT for the treatment of lung or liver oligometastases from various retrospective series and prospective trials, relatively little information has been accumulated for the treatment of oligometastases at sites other than the lungs and liver, particularly for sequential oligometastases in multiple organs. Oligometastases with primary lesions controlled is called “oligo-recurrence.” We describe herein the case of a lung cancer patient who developed repeated oligo-recurrence at multiple sites that were each controlled by radical radiotherapy and achieved long-term survival and discuss the merits of locally aggressive radiotherapy for this type of disease condition with reviewing the literature. Although further investigation should be undertaken to clarify the benefits, objectives, and methods of SBRT for the treatment of oligometastases, we believe utilization of SBRT may be worthwhile for patients with remote metastases who hope for treatment to acquire better local control and possible longer survival.http://dx.doi.org/10.1155/2012/713073
spellingShingle Hiroshi Onishi
Masatoki Ozaki
Kengo Kuriyama
Takafumi Komiyama
Kan Marino
Masayuki Araya
Ryo Saito
Shinichi Aoki
Yoshiyasu Maehata
Licht Tominaga
Mitsuhiko Oguri
Iori Watanabe
Kojiro Onohara
Meguru Watanabe
Naoki Sano
Tsutomu Araki
Stereotactic Body Radiotherapy for Metachronous Multisite Oligo-Recurrence: A Long-Surviving Case with Sequential Oligo-Recurrence in Four Different Organs Treated Using Locally Radical Radiotherapy and a Review of the Literature
Pulmonary Medicine
title Stereotactic Body Radiotherapy for Metachronous Multisite Oligo-Recurrence: A Long-Surviving Case with Sequential Oligo-Recurrence in Four Different Organs Treated Using Locally Radical Radiotherapy and a Review of the Literature
title_full Stereotactic Body Radiotherapy for Metachronous Multisite Oligo-Recurrence: A Long-Surviving Case with Sequential Oligo-Recurrence in Four Different Organs Treated Using Locally Radical Radiotherapy and a Review of the Literature
title_fullStr Stereotactic Body Radiotherapy for Metachronous Multisite Oligo-Recurrence: A Long-Surviving Case with Sequential Oligo-Recurrence in Four Different Organs Treated Using Locally Radical Radiotherapy and a Review of the Literature
title_full_unstemmed Stereotactic Body Radiotherapy for Metachronous Multisite Oligo-Recurrence: A Long-Surviving Case with Sequential Oligo-Recurrence in Four Different Organs Treated Using Locally Radical Radiotherapy and a Review of the Literature
title_short Stereotactic Body Radiotherapy for Metachronous Multisite Oligo-Recurrence: A Long-Surviving Case with Sequential Oligo-Recurrence in Four Different Organs Treated Using Locally Radical Radiotherapy and a Review of the Literature
title_sort stereotactic body radiotherapy for metachronous multisite oligo recurrence a long surviving case with sequential oligo recurrence in four different organs treated using locally radical radiotherapy and a review of the literature
url http://dx.doi.org/10.1155/2012/713073
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