First Case of Tracheobronchopathia Osteochondroplastica in an 82‐Year‐Old Patient From Saudi Arabia
ABSTRACT Background Tracheobronchopathia osteochondroplastica (TPO) is a benign tracheobronchial disorder characterized by the presence of osseous or cartilaginous nodules, typically affecting the proximal large airways while sparing the posterior membranous trachea. Around 600 cases has been docume...
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| Format: | Article |
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Wiley
2025-02-01
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| Series: | Laryngoscope Investigative Otolaryngology |
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| Online Access: | https://doi.org/10.1002/lio2.70093 |
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| author | Mohammed Hady Albitar Nida Mariyam Seba Albitar Reem Warrar Anas Sultan Sarmad Chaudhry Abdullah AlMahmoud |
| author_facet | Mohammed Hady Albitar Nida Mariyam Seba Albitar Reem Warrar Anas Sultan Sarmad Chaudhry Abdullah AlMahmoud |
| author_sort | Mohammed Hady Albitar |
| collection | DOAJ |
| description | ABSTRACT Background Tracheobronchopathia osteochondroplastica (TPO) is a benign tracheobronchial disorder characterized by the presence of osseous or cartilaginous nodules, typically affecting the proximal large airways while sparing the posterior membranous trachea. Around 600 cases has been documented worldwide for this rare disorder. While most cases are asymptomatic, some patients may exhibit symptoms such as dyspnea and chronic cough. These symptoms could be attributed to either the ulceration of the nodules or the onset of an acute infection. As it is a vague and rare disease, TPO goes undiagnosed in most cases. Case Description This case represents an 82‐year‐old male with ischemic cardiomyopathy and a history of colon cancer who presented with a six‐month history of mild hemoptysis, occasional cough, and wheezing. Laboratory tests were normal except for a positive PPD test. Imaging showed tracheal thickening with nodularity and calcification, and bronchoscopy confirmed the diagnosis. The patient was managed with symptomatic treatment and close follow‐up. Over 2 years, he remained stable, experiencing only two self‐limiting hemoptysis episodes with resolution of other symptoms. Conclusion This is the first case of TPO reported in Saudi Arabia. Given its nonspecific presentation, clinicians consider TPO as a differential diagnosis for patients with recurrent respiratory symptoms that do not respond to standard medical treatment. Level of Evidence 4. |
| format | Article |
| id | doaj-art-ef775e2f159e498b8454432a0970bd5f |
| institution | DOAJ |
| issn | 2378-8038 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Wiley |
| record_format | Article |
| series | Laryngoscope Investigative Otolaryngology |
| spelling | doaj-art-ef775e2f159e498b8454432a0970bd5f2025-08-20T03:04:53ZengWileyLaryngoscope Investigative Otolaryngology2378-80382025-02-01101n/an/a10.1002/lio2.70093First Case of Tracheobronchopathia Osteochondroplastica in an 82‐Year‐Old Patient From Saudi ArabiaMohammed Hady Albitar0Nida Mariyam1Seba Albitar2Reem Warrar3Anas Sultan4Sarmad Chaudhry5Abdullah AlMahmoud6College of Medicine Alfaisal University Riyadh Saudi ArabiaCollege of Medicine Alfaisal University Riyadh Saudi ArabiaCollege of Medicine Alfaisal University Riyadh Saudi ArabiaDepartment of Clinical Pathology King Saud Medical City Riyadh Saudi ArabiaDepartment of Internal Medicine Pulmonary Division, King Faisal Specialist Hospital and Research Centre Jeddah Saudi ArabiaDepartment of Internal Medicine Pulmonary Division, King Faisal Specialist Hospital and Research Centre Jeddah Saudi ArabiaDepartment of Internal Medicine Gastroenterology, Dr. Soliman Fakeeh Hospital Jeddah Saudi ArabiaABSTRACT Background Tracheobronchopathia osteochondroplastica (TPO) is a benign tracheobronchial disorder characterized by the presence of osseous or cartilaginous nodules, typically affecting the proximal large airways while sparing the posterior membranous trachea. Around 600 cases has been documented worldwide for this rare disorder. While most cases are asymptomatic, some patients may exhibit symptoms such as dyspnea and chronic cough. These symptoms could be attributed to either the ulceration of the nodules or the onset of an acute infection. As it is a vague and rare disease, TPO goes undiagnosed in most cases. Case Description This case represents an 82‐year‐old male with ischemic cardiomyopathy and a history of colon cancer who presented with a six‐month history of mild hemoptysis, occasional cough, and wheezing. Laboratory tests were normal except for a positive PPD test. Imaging showed tracheal thickening with nodularity and calcification, and bronchoscopy confirmed the diagnosis. The patient was managed with symptomatic treatment and close follow‐up. Over 2 years, he remained stable, experiencing only two self‐limiting hemoptysis episodes with resolution of other symptoms. Conclusion This is the first case of TPO reported in Saudi Arabia. Given its nonspecific presentation, clinicians consider TPO as a differential diagnosis for patients with recurrent respiratory symptoms that do not respond to standard medical treatment. Level of Evidence 4.https://doi.org/10.1002/lio2.70093bronchoscopyhemoptysislarge airway diseaseTPOtracheal stenosis |
| spellingShingle | Mohammed Hady Albitar Nida Mariyam Seba Albitar Reem Warrar Anas Sultan Sarmad Chaudhry Abdullah AlMahmoud First Case of Tracheobronchopathia Osteochondroplastica in an 82‐Year‐Old Patient From Saudi Arabia Laryngoscope Investigative Otolaryngology bronchoscopy hemoptysis large airway disease TPO tracheal stenosis |
| title | First Case of Tracheobronchopathia Osteochondroplastica in an 82‐Year‐Old Patient From Saudi Arabia |
| title_full | First Case of Tracheobronchopathia Osteochondroplastica in an 82‐Year‐Old Patient From Saudi Arabia |
| title_fullStr | First Case of Tracheobronchopathia Osteochondroplastica in an 82‐Year‐Old Patient From Saudi Arabia |
| title_full_unstemmed | First Case of Tracheobronchopathia Osteochondroplastica in an 82‐Year‐Old Patient From Saudi Arabia |
| title_short | First Case of Tracheobronchopathia Osteochondroplastica in an 82‐Year‐Old Patient From Saudi Arabia |
| title_sort | first case of tracheobronchopathia osteochondroplastica in an 82 year old patient from saudi arabia |
| topic | bronchoscopy hemoptysis large airway disease TPO tracheal stenosis |
| url | https://doi.org/10.1002/lio2.70093 |
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