THE ANTI-TUBERCULOSIS ANTIBIOTIC OF RIFAPENTINE: PERSPECTIVES OF CLINICAL USE

Anti-tuberculosis chemotherapy makes a main component of therapy and involves the long-term treatment with the optimal combination of drugs. Tuberculosis incidence has been noted to be high in the risk groups (those receiving immunosuppressive therapy, people living with HIV, etc.); such patients ar...

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Main Authors: A. G. Samoylova, E. I. Veselova, O. V. Lovacheva, G. D. Kaminsky
Format: Article
Language:Russian
Published: New Terra Publishing House 2019-01-01
Series:Туберкулез и болезни лёгких
Subjects:
Online Access:https://www.tibl-journal.com/jour/article/view/1204
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author A. G. Samoylova
E. I. Veselova
O. V. Lovacheva
G. D. Kaminsky
author_facet A. G. Samoylova
E. I. Veselova
O. V. Lovacheva
G. D. Kaminsky
author_sort A. G. Samoylova
collection DOAJ
description Anti-tuberculosis chemotherapy makes a main component of therapy and involves the long-term treatment with the optimal combination of drugs. Tuberculosis incidence has been noted to be high in the risk groups (those receiving immunosuppressive therapy, people living with HIV, etc.); such patients are treated for their main disease in addition to anti-tuberculosis chemotherapy. A large number of drugs used simultaneously in treatment regimens can reduce patient's adherence to treatment, deteriorate drug tolerance and increase the frequency of adverse reactions. Using slow-release drugs within treatment regimens is one of the ways to reduce polypragmasy. One of them is rifapentine, recommended in the Russian Federation for the treatment of latent tuberculosis infection in patients with HIV infection.The review presents information about the efficacy, tolerability and safety of rifapentine within treatment regimens for active and latent tuberculosis infection.
format Article
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institution OA Journals
issn 2075-1230
2542-1506
language Russian
publishDate 2019-01-01
publisher New Terra Publishing House
record_format Article
series Туберкулез и болезни лёгких
spelling doaj-art-ef6be59d87d6445785e4e42d03837cc72025-08-20T02:05:49ZrusNew Terra Publishing HouseТуберкулез и болезни лёгких2075-12302542-15062019-01-019612556110.21292/2075-1230-2018-96-12-55-611204THE ANTI-TUBERCULOSIS ANTIBIOTIC OF RIFAPENTINE: PERSPECTIVES OF CLINICAL USEA. G. Samoylova0E. I. Veselova1O. V. Lovacheva2G. D. Kaminsky3National Medical Research Center of Phthisiopulmonology and Infectious DiseasesNational Medical Research Center of Phthisiopulmonology and Infectious DiseasesNational Medical Research Center of Phthisiopulmonology and Infectious DiseasesNational Medical Research Center of Phthisiopulmonology and Infectious DiseasesAnti-tuberculosis chemotherapy makes a main component of therapy and involves the long-term treatment with the optimal combination of drugs. Tuberculosis incidence has been noted to be high in the risk groups (those receiving immunosuppressive therapy, people living with HIV, etc.); such patients are treated for their main disease in addition to anti-tuberculosis chemotherapy. A large number of drugs used simultaneously in treatment regimens can reduce patient's adherence to treatment, deteriorate drug tolerance and increase the frequency of adverse reactions. Using slow-release drugs within treatment regimens is one of the ways to reduce polypragmasy. One of them is rifapentine, recommended in the Russian Federation for the treatment of latent tuberculosis infection in patients with HIV infection.The review presents information about the efficacy, tolerability and safety of rifapentine within treatment regimens for active and latent tuberculosis infection.https://www.tibl-journal.com/jour/article/view/1204rifapentineactive and latent tuberculous infectionanti-tuberculosis chemotherapy
spellingShingle A. G. Samoylova
E. I. Veselova
O. V. Lovacheva
G. D. Kaminsky
THE ANTI-TUBERCULOSIS ANTIBIOTIC OF RIFAPENTINE: PERSPECTIVES OF CLINICAL USE
Туберкулез и болезни лёгких
rifapentine
active and latent tuberculous infection
anti-tuberculosis chemotherapy
title THE ANTI-TUBERCULOSIS ANTIBIOTIC OF RIFAPENTINE: PERSPECTIVES OF CLINICAL USE
title_full THE ANTI-TUBERCULOSIS ANTIBIOTIC OF RIFAPENTINE: PERSPECTIVES OF CLINICAL USE
title_fullStr THE ANTI-TUBERCULOSIS ANTIBIOTIC OF RIFAPENTINE: PERSPECTIVES OF CLINICAL USE
title_full_unstemmed THE ANTI-TUBERCULOSIS ANTIBIOTIC OF RIFAPENTINE: PERSPECTIVES OF CLINICAL USE
title_short THE ANTI-TUBERCULOSIS ANTIBIOTIC OF RIFAPENTINE: PERSPECTIVES OF CLINICAL USE
title_sort anti tuberculosis antibiotic of rifapentine perspectives of clinical use
topic rifapentine
active and latent tuberculous infection
anti-tuberculosis chemotherapy
url https://www.tibl-journal.com/jour/article/view/1204
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AT gdkaminsky theantituberculosisantibioticofrifapentineperspectivesofclinicaluse
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