Efficacy of daclatasvir and asunaprevir for viral hepatitis С in two donor lung recipients
Aim. To estimate efficacy and safety of direct antiviral drugs for hepatitis C treatment in donor lung recipients. Key points. The first cases in Russian literature and one of the first-ever cases of hepatitis C treatment by direct antiviral agents in lung transplant recipients are presented. Combi...
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| Format: | Article |
| Language: | Russian |
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Gastro LLC
2018-08-01
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| Series: | Российский журнал гастроэнтерологии, гепатологии, колопроктологии |
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| Online Access: | https://www.gastro-j.ru/jour/article/view/182 |
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| author | D. T. Abdurakhmanov Ye. . Sidorova I. N. Tikhonov N. A. Mukhin V. T. Ivashkin |
| author_facet | D. T. Abdurakhmanov Ye. . Sidorova I. N. Tikhonov N. A. Mukhin V. T. Ivashkin |
| author_sort | D. T. Abdurakhmanov |
| collection | DOAJ |
| description | Aim. To estimate efficacy and safety of direct antiviral drugs for hepatitis C treatment in donor lung recipients. Key points. The first cases in Russian literature and one of the first-ever cases of hepatitis C treatment by direct antiviral agents in lung transplant recipients are presented. Combined therapy by asunaprevir and daclatasvir for 24 weeks resulted in sustained virologic response. No significant adverse effects on drug to drug interactions, except for mild and controllable alteration of tacrolimus blood level, were noted. Conclusion. Daclatasvir and asunaprevir combination is effective and safe treatment mode for hepatitis C in donor lung recipients |
| format | Article |
| id | doaj-art-ef610a0368f747239f8f36db1d840a4e |
| institution | Kabale University |
| issn | 1382-4376 2658-6673 |
| language | Russian |
| publishDate | 2018-08-01 |
| publisher | Gastro LLC |
| record_format | Article |
| series | Российский журнал гастроэнтерологии, гепатологии, колопроктологии |
| spelling | doaj-art-ef610a0368f747239f8f36db1d840a4e2025-02-10T16:14:29ZrusGastro LLCРоссийский журнал гастроэнтерологии, гепатологии, колопроктологии1382-43762658-66732018-08-01275656810.22416/1382-4376-2017-27-5-65-68182Efficacy of daclatasvir and asunaprevir for viral hepatitis С in two donor lung recipientsD. T. Abdurakhmanov0Ye. . Sidorova1I. N. Tikhonov2N. A. Mukhin3V. T. Ivashkin4Federal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical UniversityFederal state educational government-financed institution of higher education «Lomonosov Moscow State University»Federal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical UniversityFederal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical UniversityFederal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical UniversityAim. To estimate efficacy and safety of direct antiviral drugs for hepatitis C treatment in donor lung recipients. Key points. The first cases in Russian literature and one of the first-ever cases of hepatitis C treatment by direct antiviral agents in lung transplant recipients are presented. Combined therapy by asunaprevir and daclatasvir for 24 weeks resulted in sustained virologic response. No significant adverse effects on drug to drug interactions, except for mild and controllable alteration of tacrolimus blood level, were noted. Conclusion. Daclatasvir and asunaprevir combination is effective and safe treatment mode for hepatitis C in donor lung recipientshttps://www.gastro-j.ru/jour/article/view/182противовирусные препаратыгепатит странсплантация легкихдаклатасвирасунапревир |
| spellingShingle | D. T. Abdurakhmanov Ye. . Sidorova I. N. Tikhonov N. A. Mukhin V. T. Ivashkin Efficacy of daclatasvir and asunaprevir for viral hepatitis С in two donor lung recipients Российский журнал гастроэнтерологии, гепатологии, колопроктологии противовирусные препараты гепатит с трансплантация легких даклатасвир асунапревир |
| title | Efficacy of daclatasvir and asunaprevir for viral hepatitis С in two donor lung recipients |
| title_full | Efficacy of daclatasvir and asunaprevir for viral hepatitis С in two donor lung recipients |
| title_fullStr | Efficacy of daclatasvir and asunaprevir for viral hepatitis С in two donor lung recipients |
| title_full_unstemmed | Efficacy of daclatasvir and asunaprevir for viral hepatitis С in two donor lung recipients |
| title_short | Efficacy of daclatasvir and asunaprevir for viral hepatitis С in two donor lung recipients |
| title_sort | efficacy of daclatasvir and asunaprevir for viral hepatitis с in two donor lung recipients |
| topic | противовирусные препараты гепатит с трансплантация легких даклатасвир асунапревир |
| url | https://www.gastro-j.ru/jour/article/view/182 |
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