Metabolic landscape uncovers remodeling of T cell immunity affected by fatty acid desaturase in Parkinson’s disease at single-cell resolution
Abstract Background Peripheral activated T cells cross the blood–brain barrier, partake in neuroinflammation, and induce dopaminergic neuron degeneration through characteristics such as cell adhesion and immune response in Parkinson’s disease (PD). Metabolic activity, which can regulate and be regul...
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| Main Authors: | Shi Yan, Xue Zhao, Yao Si, Xinyu Zhang, Di Wang, Lifen Yao, Linlin Sun |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-08-01
|
| Series: | BMC Biology |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12915-025-02358-w |
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