Ketone body oxidation increases cardiac endothelial cell proliferation

Ketone body oxidation increases cardiac endothelial cell proliferation

Abstract Blood vessel formation is dependent on metabolic adaption in endothelial cells. Glucose and fatty acids are essential substrates for ATP and biomass production; however, the metabolism of other substrates remains poorly understood. Ketone bodies are important nutrients for cardiomyocytes du...

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Bibliographic Details
Main Authors: Eva‐Maria Weis, Patrycja Puchalska, Alisa B Nelson, Jacqueline Taylor, Iris Moll, Sana S Hasan, Matthias Dewenter, Marco Hagenmüller, Thomas Fleming, Gernot Poschet, Agnes Hotz‐Wagenblatt, Johannes Backs, Peter A Crawford, Andreas Fischer
Format: Article
Language:English
Published: Springer Nature 2022-02-01
Series:EMBO Molecular Medicine
Subjects:
angiogenesis
endothelial cell
heart
ketogenic diet
ketone bodies
Online Access:https://doi.org/10.15252/emmm.202114753
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