Transvaginal ultrasound and magnetic resonance imaging in the diagnosis of endometrioma: a systematic review and meta-analysis of diagnostic test accuracy studies*
Introduction The diagnosis of endometriomas in patients with endometriosis is of primary importance because it influences the management and prognosis of infertility and pain. Imaging techniques are evolving constantly. This study aimed to systematically assess the diagnostic accuracy of transvagina...
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Taylor & Francis Group
2024-12-01
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| Series: | Journal of Obstetrics and Gynaecology |
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| Online Access: | https://www.tandfonline.com/doi/10.1080/01443615.2024.2311664 |
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| author | Fleur Serge Kanti Rose Gorak Savard Frédéric Bergeron Hervé Tchala Vignon Zomahoun Antoine Netter Sarah Maheux-Lacroix |
| author_facet | Fleur Serge Kanti Rose Gorak Savard Frédéric Bergeron Hervé Tchala Vignon Zomahoun Antoine Netter Sarah Maheux-Lacroix |
| author_sort | Fleur Serge Kanti |
| collection | DOAJ |
| description | Introduction The diagnosis of endometriomas in patients with endometriosis is of primary importance because it influences the management and prognosis of infertility and pain. Imaging techniques are evolving constantly. This study aimed to systematically assess the diagnostic accuracy of transvaginal ultrasound (TVUS) and magnetic resonance imaging (MRI) in detecting endometrioma using the surgical visualisation of lesions with or without histopathological confirmation as reference standards in patients of reproductive age with suspected endometriosis.Methods PubMed, Embase, Web of Science, Cumulative Index to Nursing and Allied Health Literature and ClinicalTrials.gov databases were searched from their inception to 12 October 2022, using a manual search for additional articles. Two authors independently performed title, abstract and full-text screening of the identified records, extracted study details and quantitative data and assessed the quality of the studies using the ‘Quality Assessment of Diagnostic Accuracy Study 2’ tool. Bivariate random-effects models were used to determine the pooled sensitivity and specificity, compare the two imaging modalities and evaluate the sources of heterogeneity.Results Sixteen prospective studies (10 assessing TVUS, 4 assessing MRI and 2 assessing both TVUS and MRI) were included, representing 1976 participants. Pooled TVUS and MRI sensitivities for endometrioma were 0.89 (95% confidence interval ‘CI’, 0.86–0.92) and 0.94 (95% CI, 0.74–0.99), respectively (indirect comparison p-value of 0.47). Pooled TVUS and MRI specificities for endometrioma were 0.95 (95% CI, 0.92–0.97) and 0.94 (95% CI, 0.89–0.97), respectively (indirect comparison p-value of 0.51). These studies had a high or unclear risk of bias. A direct comparison (all participants undergoing TVUS and MRI) of the modalities was available in only two studies.Conclusion TVUS and MRI have high accuracy for diagnosing endometriomas; however, high-quality studies comparing the two modalities are lacking. |
| format | Article |
| id | doaj-art-ef54f9afbd7a4f22a5e8fa4366d541a8 |
| institution | Kabale University |
| issn | 0144-3615 1364-6893 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Taylor & Francis Group |
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| series | Journal of Obstetrics and Gynaecology |
| spelling | doaj-art-ef54f9afbd7a4f22a5e8fa4366d541a82025-01-09T12:13:17ZengTaylor & Francis GroupJournal of Obstetrics and Gynaecology0144-36151364-68932024-12-0144110.1080/01443615.2024.2311664Transvaginal ultrasound and magnetic resonance imaging in the diagnosis of endometrioma: a systematic review and meta-analysis of diagnostic test accuracy studies*Fleur Serge Kanti0Rose Gorak Savard1Frédéric Bergeron2Hervé Tchala Vignon Zomahoun3Antoine Netter4Sarah Maheux-Lacroix5Centre de recherche du CHU de Québec – Université Laval, Quebec City, CanadaCentre de recherche du CHU de Québec – Université Laval, Quebec City, CanadaUniversité Laval, Quebec City, CanadaCentre de recherche sur les soins et les services de première ligne (CERSSPL) – Université Laval, Quebec City, CanadaDepartment of Gynecology-Obstetrics and Reproductive Medicine, AP-HM, La Conception Hospital, Marseille, FranceCentre de recherche du CHU de Québec – Université Laval, Quebec City, CanadaIntroduction The diagnosis of endometriomas in patients with endometriosis is of primary importance because it influences the management and prognosis of infertility and pain. Imaging techniques are evolving constantly. This study aimed to systematically assess the diagnostic accuracy of transvaginal ultrasound (TVUS) and magnetic resonance imaging (MRI) in detecting endometrioma using the surgical visualisation of lesions with or without histopathological confirmation as reference standards in patients of reproductive age with suspected endometriosis.Methods PubMed, Embase, Web of Science, Cumulative Index to Nursing and Allied Health Literature and ClinicalTrials.gov databases were searched from their inception to 12 October 2022, using a manual search for additional articles. Two authors independently performed title, abstract and full-text screening of the identified records, extracted study details and quantitative data and assessed the quality of the studies using the ‘Quality Assessment of Diagnostic Accuracy Study 2’ tool. Bivariate random-effects models were used to determine the pooled sensitivity and specificity, compare the two imaging modalities and evaluate the sources of heterogeneity.Results Sixteen prospective studies (10 assessing TVUS, 4 assessing MRI and 2 assessing both TVUS and MRI) were included, representing 1976 participants. Pooled TVUS and MRI sensitivities for endometrioma were 0.89 (95% confidence interval ‘CI’, 0.86–0.92) and 0.94 (95% CI, 0.74–0.99), respectively (indirect comparison p-value of 0.47). Pooled TVUS and MRI specificities for endometrioma were 0.95 (95% CI, 0.92–0.97) and 0.94 (95% CI, 0.89–0.97), respectively (indirect comparison p-value of 0.51). These studies had a high or unclear risk of bias. A direct comparison (all participants undergoing TVUS and MRI) of the modalities was available in only two studies.Conclusion TVUS and MRI have high accuracy for diagnosing endometriomas; however, high-quality studies comparing the two modalities are lacking.https://www.tandfonline.com/doi/10.1080/01443615.2024.2311664Diagnostic test accuracyendometriomaendometriosismagnetic resonance imagingtransvaginal ultrasound |
| spellingShingle | Fleur Serge Kanti Rose Gorak Savard Frédéric Bergeron Hervé Tchala Vignon Zomahoun Antoine Netter Sarah Maheux-Lacroix Transvaginal ultrasound and magnetic resonance imaging in the diagnosis of endometrioma: a systematic review and meta-analysis of diagnostic test accuracy studies* Journal of Obstetrics and Gynaecology Diagnostic test accuracy endometrioma endometriosis magnetic resonance imaging transvaginal ultrasound |
| title | Transvaginal ultrasound and magnetic resonance imaging in the diagnosis of endometrioma: a systematic review and meta-analysis of diagnostic test accuracy studies* |
| title_full | Transvaginal ultrasound and magnetic resonance imaging in the diagnosis of endometrioma: a systematic review and meta-analysis of diagnostic test accuracy studies* |
| title_fullStr | Transvaginal ultrasound and magnetic resonance imaging in the diagnosis of endometrioma: a systematic review and meta-analysis of diagnostic test accuracy studies* |
| title_full_unstemmed | Transvaginal ultrasound and magnetic resonance imaging in the diagnosis of endometrioma: a systematic review and meta-analysis of diagnostic test accuracy studies* |
| title_short | Transvaginal ultrasound and magnetic resonance imaging in the diagnosis of endometrioma: a systematic review and meta-analysis of diagnostic test accuracy studies* |
| title_sort | transvaginal ultrasound and magnetic resonance imaging in the diagnosis of endometrioma a systematic review and meta analysis of diagnostic test accuracy studies |
| topic | Diagnostic test accuracy endometrioma endometriosis magnetic resonance imaging transvaginal ultrasound |
| url | https://www.tandfonline.com/doi/10.1080/01443615.2024.2311664 |
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