Clinical Applications and Potential Mechanism of Cold Acclimation Therapy

Yongxing Wang,1,* Yajun Wang,1,* Dezhi Han,2 Weijing Sun,2 Yaqun Qiao,1 Conghui Wang,3 Xu Zhang,1 Jinlong Xu2 1Department of General Surgery, The 969th Hospital of the Chinese People’s Liberation Army Joint Logistics Support Force, Hohhot, Inner Mongolia, 010051, People’s Rep...

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Main Authors: Wang Y, Han D, Sun W, Qiao Y, Wang C, Zhang X, Xu J
Format: Article
Language:English
Published: Dove Medical Press 2025-07-01
Series:Journal of Multidisciplinary Healthcare
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Online Access:https://www.dovepress.com/clinical-applications-and-potential-mechanism-of-cold-acclimation-ther-peer-reviewed-fulltext-article-JMDH
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author Wang Y
Wang Y
Han D
Sun W
Qiao Y
Wang C
Zhang X
Xu J
author_facet Wang Y
Wang Y
Han D
Sun W
Qiao Y
Wang C
Zhang X
Xu J
author_sort Wang Y
collection DOAJ
description Yongxing Wang,1,* Yajun Wang,1,* Dezhi Han,2 Weijing Sun,2 Yaqun Qiao,1 Conghui Wang,3 Xu Zhang,1 Jinlong Xu2 1Department of General Surgery, The 969th Hospital of the Chinese People’s Liberation Army Joint Logistics Support Force, Hohhot, Inner Mongolia, 010051, People’s Republic of China; 2Department of Burn and Plastic Surgery, The 969th Hospital of the Chinese People’s Liberation Army Joint Logistics Support Force, Hohhot, Inner Mongolia, 010051, People’s Republic of China; 3Clinical Lab, The 969th Hospital of the Chinese People’s Liberation Army Joint Logistics Support Force, Hohhot, Inner Mongolia, 010051, People’s Republic of China*These authors contributed equally to this workCorrespondence: Jinlong Xu, Department of Burn and Plastic Surgery, The 969th Hospital of the Chinese People’s Liberation Army Joint Logistics Support Force, No. 111 Aimin Road, Hohhot, 010051, People’s Republic of China, Tel +8618548164089, Email xujinlong1986228@163.comAbstract: Cold acclimation therapy has emerged as a notable therapeutic approach with physical therapy and clinical medicine. Driven by the rising demand for effective pain management, sports recovery, and inflammation control, several studies have examined the physiological mechanisms and diverse applications of cold acclimation therapy. Current research shows that cold acclimation therapy can effectively alleviate both acute and chronic pain, promote post-exercise recovery, and mitigate inflammatory responses. Despite its potential, challenges persist in its clinical application, including the determination of precise clinical indications, optimal timing of intervention, and potential adverse effects. This review summarizes the fundamental principles, clinical applications, current research progress, and future potential of cold acclimation therapy, aiming to provide a reference for clinical practice. Furthermore, the future applications of cold acclimation therapy in medical practice is discussed, emphasizing its importance and development prospects in modern healthcare.Keywords: cold acclimation therapy, inflammation control, pain management, physical therapy, sports recovery
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spelling doaj-art-ef5083aaebcb417b8e3ebe3044a68cbe2025-08-20T03:51:08ZengDove Medical PressJournal of Multidisciplinary Healthcare1178-23902025-07-01Volume 18Issue 141134120104957Clinical Applications and Potential Mechanism of Cold Acclimation TherapyWang Y0Wang Y1Han D2Sun W3Qiao Y4Wang C5Zhang X6Xu J7Department of General SurgeryDepartment of General SurgeryDepartment of Burn and Plastic SurgeryDepartment of Burn and Plastic SurgeryDepartment of General SurgeryClinical LabDepartment of General SurgeryDepartment of Burn and Plastic SurgeryYongxing Wang,1,* Yajun Wang,1,* Dezhi Han,2 Weijing Sun,2 Yaqun Qiao,1 Conghui Wang,3 Xu Zhang,1 Jinlong Xu2 1Department of General Surgery, The 969th Hospital of the Chinese People’s Liberation Army Joint Logistics Support Force, Hohhot, Inner Mongolia, 010051, People’s Republic of China; 2Department of Burn and Plastic Surgery, The 969th Hospital of the Chinese People’s Liberation Army Joint Logistics Support Force, Hohhot, Inner Mongolia, 010051, People’s Republic of China; 3Clinical Lab, The 969th Hospital of the Chinese People’s Liberation Army Joint Logistics Support Force, Hohhot, Inner Mongolia, 010051, People’s Republic of China*These authors contributed equally to this workCorrespondence: Jinlong Xu, Department of Burn and Plastic Surgery, The 969th Hospital of the Chinese People’s Liberation Army Joint Logistics Support Force, No. 111 Aimin Road, Hohhot, 010051, People’s Republic of China, Tel +8618548164089, Email xujinlong1986228@163.comAbstract: Cold acclimation therapy has emerged as a notable therapeutic approach with physical therapy and clinical medicine. Driven by the rising demand for effective pain management, sports recovery, and inflammation control, several studies have examined the physiological mechanisms and diverse applications of cold acclimation therapy. Current research shows that cold acclimation therapy can effectively alleviate both acute and chronic pain, promote post-exercise recovery, and mitigate inflammatory responses. Despite its potential, challenges persist in its clinical application, including the determination of precise clinical indications, optimal timing of intervention, and potential adverse effects. This review summarizes the fundamental principles, clinical applications, current research progress, and future potential of cold acclimation therapy, aiming to provide a reference for clinical practice. Furthermore, the future applications of cold acclimation therapy in medical practice is discussed, emphasizing its importance and development prospects in modern healthcare.Keywords: cold acclimation therapy, inflammation control, pain management, physical therapy, sports recoveryhttps://www.dovepress.com/clinical-applications-and-potential-mechanism-of-cold-acclimation-ther-peer-reviewed-fulltext-article-JMDHCold acclimation therapyinflammation controlpain managementphysical therapysports recovery
spellingShingle Wang Y
Wang Y
Han D
Sun W
Qiao Y
Wang C
Zhang X
Xu J
Clinical Applications and Potential Mechanism of Cold Acclimation Therapy
Journal of Multidisciplinary Healthcare
Cold acclimation therapy
inflammation control
pain management
physical therapy
sports recovery
title Clinical Applications and Potential Mechanism of Cold Acclimation Therapy
title_full Clinical Applications and Potential Mechanism of Cold Acclimation Therapy
title_fullStr Clinical Applications and Potential Mechanism of Cold Acclimation Therapy
title_full_unstemmed Clinical Applications and Potential Mechanism of Cold Acclimation Therapy
title_short Clinical Applications and Potential Mechanism of Cold Acclimation Therapy
title_sort clinical applications and potential mechanism of cold acclimation therapy
topic Cold acclimation therapy
inflammation control
pain management
physical therapy
sports recovery
url https://www.dovepress.com/clinical-applications-and-potential-mechanism-of-cold-acclimation-ther-peer-reviewed-fulltext-article-JMDH
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