Obesity-induced adipocytes promote diabetes mellitus by regulating β islet cell function through exosome miR-138-5p

Abstract Insulin dysfunction can lead to type 1 diabetes mellitus (T1DM), inducing an increase in blood glucose levels. Unfortunately, there remains a need for more effective clinical treatments for DM. Obesity is closely associated with islet dysfunction, but these inside mechanisms remain unclear....

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Bibliographic Details
Main Authors: Shihong Fan, Nengjuan Li
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
Subjects:
Online Access:https://doi.org/10.1038/s41598-025-01564-4
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