Advancements in Antioxidant-Based Therapeutics for Spinal Cord Injury: A Critical Review of Strategies and Combination Approaches

Advancements in Antioxidant-Based Therapeutics for Spinal Cord Injury: A Critical Review of Strategies and Combination Approaches

Spinal cord injury (SCI) initiates a cascade of secondary damage driven by oxidative stress, characterized by the excessive production of reactive oxygen species and other reactive molecules, which exacerbate cellular and tissue damage through the activation of deleterious signaling pathways. This r...

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Bibliographic Details
Main Authors: Yang-Jin Shen, Yin-Cheng Huang, Yi-Chuan Cheng
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Antioxidants
Subjects:
spinal cord injury (SCI)
oxidative stress
antioxidant therapy
endogenous antioxidants
natural compounds
pharmacological compounds
Online Access:https://www.mdpi.com/2076-3921/14/1/17
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