Evaluation of the Effectiveness of Nonspecific Medical Protection Against Diseased, Caused of Ebola Virus
The article presents an analysis of research evaluating the effectiveness of nonspecific means of emergency prevention and treatment of Ebola virus disease. It considers the most significant results of preclinical and clinical trials of nonspecific therapeutics for the causative agent of Ebola hemor...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | Russian |
| Published: |
LLC "Publishing House OKI"
2020-05-01
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| Series: | Антибиотики и Химиотерапия |
| Subjects: | |
| Online Access: | https://www.antibiotics-chemotherapy.ru/jour/article/view/186 |
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| _version_ | 1849693082973372416 |
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| author | T. E. Sizikova v. N. Lebedev A. A. Petrov S. V. Borisevich |
| author_facet | T. E. Sizikova v. N. Lebedev A. A. Petrov S. V. Borisevich |
| author_sort | T. E. Sizikova |
| collection | DOAJ |
| description | The article presents an analysis of research evaluating the effectiveness of nonspecific means of emergency prevention and treatment of Ebola virus disease. It considers the most significant results of preclinical and clinical trials of nonspecific therapeutics for the causative agent of Ebola hemorrhagic fever, as well as the prospects for their use in healthcare practice at present. It has been established that the general tendency to create nonspecific means of prevention and treatment of Ebola virus disease is not the development of new drugs, but the attempts to detect the antiviral activity of already known drugs that previously had a different purpose. Favipiravir is considered as the most effective nonspecific therapeutic against Ebola virus disease. |
| format | Article |
| id | doaj-art-ef458d3339b84bd3a3e7fe6846e95257 |
| institution | DOAJ |
| issn | 0235-2990 |
| language | Russian |
| publishDate | 2020-05-01 |
| publisher | LLC "Publishing House OKI" |
| record_format | Article |
| series | Антибиотики и Химиотерапия |
| spelling | doaj-art-ef458d3339b84bd3a3e7fe6846e952572025-08-20T03:20:32ZrusLLC "Publishing House OKI"Антибиотики и Химиотерапия0235-29902020-05-01649-10505510.24411/0235-2990-2019-10057185Evaluation of the Effectiveness of Nonspecific Medical Protection Against Diseased, Caused of Ebola VirusT. E. Sizikova0v. N. Lebedev1A. A. Petrov2S. V. Borisevich3FSBI 48 Central Research Institute of the Ministry of Defense of the Russian FederationFSBI 48 Central Research Institute of the Ministry of Defense of the Russian FederationFSBI 48 Central Research Institute of the Ministry of Defense of the Russian FederationFSBI 48 Central Research Institute of the Ministry of Defense of the Russian FederationThe article presents an analysis of research evaluating the effectiveness of nonspecific means of emergency prevention and treatment of Ebola virus disease. It considers the most significant results of preclinical and clinical trials of nonspecific therapeutics for the causative agent of Ebola hemorrhagic fever, as well as the prospects for their use in healthcare practice at present. It has been established that the general tendency to create nonspecific means of prevention and treatment of Ebola virus disease is not the development of new drugs, but the attempts to detect the antiviral activity of already known drugs that previously had a different purpose. Favipiravir is considered as the most effective nonspecific therapeutic against Ebola virus disease.https://www.antibiotics-chemotherapy.ru/jour/article/view/186ebola virus, hemorrhagic fever, therapeutic, broad-spectrum drugs, emergency prevention and treatment, favipiravir, interferon, preclinical trials, clinical trials |
| spellingShingle | T. E. Sizikova v. N. Lebedev A. A. Petrov S. V. Borisevich Evaluation of the Effectiveness of Nonspecific Medical Protection Against Diseased, Caused of Ebola Virus Антибиотики и Химиотерапия ebola virus, hemorrhagic fever, therapeutic, broad-spectrum drugs, emergency prevention and treatment, favipiravir, interferon, preclinical trials, clinical trials |
| title | Evaluation of the Effectiveness of Nonspecific Medical Protection Against Diseased, Caused of Ebola Virus |
| title_full | Evaluation of the Effectiveness of Nonspecific Medical Protection Against Diseased, Caused of Ebola Virus |
| title_fullStr | Evaluation of the Effectiveness of Nonspecific Medical Protection Against Diseased, Caused of Ebola Virus |
| title_full_unstemmed | Evaluation of the Effectiveness of Nonspecific Medical Protection Against Diseased, Caused of Ebola Virus |
| title_short | Evaluation of the Effectiveness of Nonspecific Medical Protection Against Diseased, Caused of Ebola Virus |
| title_sort | evaluation of the effectiveness of nonspecific medical protection against diseased caused of ebola virus |
| topic | ebola virus, hemorrhagic fever, therapeutic, broad-spectrum drugs, emergency prevention and treatment, favipiravir, interferon, preclinical trials, clinical trials |
| url | https://www.antibiotics-chemotherapy.ru/jour/article/view/186 |
| work_keys_str_mv | AT tesizikova evaluationoftheeffectivenessofnonspecificmedicalprotectionagainstdiseasedcausedofebolavirus AT vnlebedev evaluationoftheeffectivenessofnonspecificmedicalprotectionagainstdiseasedcausedofebolavirus AT aapetrov evaluationoftheeffectivenessofnonspecificmedicalprotectionagainstdiseasedcausedofebolavirus AT svborisevich evaluationoftheeffectivenessofnonspecificmedicalprotectionagainstdiseasedcausedofebolavirus |