CERTAIN ASPECTS OF RESPIRATORY AND DIGESTIVE TRACT INVOLVEMENT IN CYSTIC FIBROSIS IN CHILDREN
Cystic fibrosis is one of the severe childhood disorders with early manifestation of multiple organ involvement. The respiratory and digestive tracts are suffered the most, the prognosis of disease course depends on the degree of the impairment of these systems. The results of the analysis of cyst...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
"Paediatrician" Publishers LLC
2013-02-01
|
| Series: | Вопросы современной педиатрии |
| Subjects: | |
| Online Access: | https://vsp.spr-journal.ru/jour/article/view/385 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849690746187153408 |
|---|---|
| author | T. G. Vasil’eva S. N. Shishatskaya A. N. Ni |
| author_facet | T. G. Vasil’eva S. N. Shishatskaya A. N. Ni |
| author_sort | T. G. Vasil’eva |
| collection | DOAJ |
| description | Cystic fibrosis is one of the severe childhood disorders with early manifestation of multiple organ involvement. The respiratory and digestive tracts are suffered the most, the prognosis of disease course depends on the degree of the impairment of these systems. The results of the analysis of cystic fibrosis prevalence in Primorsky Krai according to the neonatal immunoreactive trypsin screening in 102 251 newborn are shown in the article. The age, sex, clinical and severity structure of cystic fibrosis was studied in 71 children. The prevalence of 13 mutations of transmembrane regulator conductance gene in 41 patients was determined. Correlations between time of pulmonary complications manifestation, P. Aeruginosa infection development, chronic hypoxemia degree, malnutrition, genetic status and severity of the disease were found. |
| format | Article |
| id | doaj-art-ef39dd2e234e482ea16fd2729931b6e9 |
| institution | DOAJ |
| issn | 1682-5527 1682-5535 |
| language | English |
| publishDate | 2013-02-01 |
| publisher | "Paediatrician" Publishers LLC |
| record_format | Article |
| series | Вопросы современной педиатрии |
| spelling | doaj-art-ef39dd2e234e482ea16fd2729931b6e92025-08-20T03:21:13Zeng"Paediatrician" Publishers LLCВопросы современной педиатрии1682-55271682-55352013-02-0112116216510.15690/vsp.v12i1.574385CERTAIN ASPECTS OF RESPIRATORY AND DIGESTIVE TRACT INVOLVEMENT IN CYSTIC FIBROSIS IN CHILDRENT. G. Vasil’eva0S. N. Shishatskaya1A. N. Ni2Territorial Centre of Specialized Medical Care, Vladivostok; Far Eastern Branch of the FSFI “Scientific Center of Family Health and Human Reproduction Problems” of the Siberian Department of RAMS, VladivostokVladivostok State Medical University, Russian FederationVladivostok State Medical UniversityCystic fibrosis is one of the severe childhood disorders with early manifestation of multiple organ involvement. The respiratory and digestive tracts are suffered the most, the prognosis of disease course depends on the degree of the impairment of these systems. The results of the analysis of cystic fibrosis prevalence in Primorsky Krai according to the neonatal immunoreactive trypsin screening in 102 251 newborn are shown in the article. The age, sex, clinical and severity structure of cystic fibrosis was studied in 71 children. The prevalence of 13 mutations of transmembrane regulator conductance gene in 41 patients was determined. Correlations between time of pulmonary complications manifestation, P. Aeruginosa infection development, chronic hypoxemia degree, malnutrition, genetic status and severity of the disease were found.https://vsp.spr-journal.ru/jour/article/view/385cystic fibrosischildrenrespiratory tractdigestive tract |
| spellingShingle | T. G. Vasil’eva S. N. Shishatskaya A. N. Ni CERTAIN ASPECTS OF RESPIRATORY AND DIGESTIVE TRACT INVOLVEMENT IN CYSTIC FIBROSIS IN CHILDREN Вопросы современной педиатрии cystic fibrosis children respiratory tract digestive tract |
| title | CERTAIN ASPECTS OF RESPIRATORY AND DIGESTIVE TRACT INVOLVEMENT IN CYSTIC FIBROSIS IN CHILDREN |
| title_full | CERTAIN ASPECTS OF RESPIRATORY AND DIGESTIVE TRACT INVOLVEMENT IN CYSTIC FIBROSIS IN CHILDREN |
| title_fullStr | CERTAIN ASPECTS OF RESPIRATORY AND DIGESTIVE TRACT INVOLVEMENT IN CYSTIC FIBROSIS IN CHILDREN |
| title_full_unstemmed | CERTAIN ASPECTS OF RESPIRATORY AND DIGESTIVE TRACT INVOLVEMENT IN CYSTIC FIBROSIS IN CHILDREN |
| title_short | CERTAIN ASPECTS OF RESPIRATORY AND DIGESTIVE TRACT INVOLVEMENT IN CYSTIC FIBROSIS IN CHILDREN |
| title_sort | certain aspects of respiratory and digestive tract involvement in cystic fibrosis in children |
| topic | cystic fibrosis children respiratory tract digestive tract |
| url | https://vsp.spr-journal.ru/jour/article/view/385 |
| work_keys_str_mv | AT tgvasileva certainaspectsofrespiratoryanddigestivetractinvolvementincysticfibrosisinchildren AT snshishatskaya certainaspectsofrespiratoryanddigestivetractinvolvementincysticfibrosisinchildren AT anni certainaspectsofrespiratoryanddigestivetractinvolvementincysticfibrosisinchildren |