ER stress and/or ER-phagy in drug resistance? Three coincidences are proof

ER stress and/or ER-phagy in drug resistance? Three coincidences are proof

Abstract Cancer is influenced by the tumor microenvironment (TME), which includes factors such as pH, hypoxia, immune cells, and blood vessels. These factors affect cancer cell growth and behavior. The tumor microenvironment triggers adaptive responses such as endoplasmic reticulum (ER) stress, unfo...

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Bibliographic Details
Main Authors: Sameer Kumar Panda, Ibone Rubio Sanchez-Pajares, Ayesha Rehman, Vitale Del Vecchio, Luigi Mele, Sandhya Chipurupalli, Nirmal Robinson, Vincenzo Desiderio
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Cell Communication and Signaling
Subjects:
ER Stress
UPR
ER-phagy
Autophagy
Drug resistance
Online Access:https://doi.org/10.1186/s12964-025-02232-w
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