Validated UV-Spectrophotometric Methods for Determination of Gemifloxacin Mesylate in Pharmaceutical Tablet Dosage Forms
Two simple, economic and accurate UV spectrophotometric methods have been developed for determination of gemifloxacin mesylate in pharmaceutical tablet formulation. The first UV-spectrophotometric method depends upon the measurement of absorption at the wavelength 263.8 nm. In second area under curv...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Wiley
2010-01-01
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| Series: | E-Journal of Chemistry |
| Online Access: | http://dx.doi.org/10.1155/2010/346847 |
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| _version_ | 1850162984425357312 |
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| author | R. Rote Ambadas P. Pingle Sunita |
| author_facet | R. Rote Ambadas P. Pingle Sunita |
| author_sort | R. Rote Ambadas |
| collection | DOAJ |
| description | Two simple, economic and accurate UV spectrophotometric methods have been developed for determination of gemifloxacin mesylate in pharmaceutical tablet formulation. The first UV-spectrophotometric method depends upon the measurement of absorption at the wavelength 263.8 nm. In second area under curve method the wavelength range for detection was selected from 268.5-258.5 nm. Beer’s law was obeyed in the range of 2 to 12 μgmL-1 for both the methods. The proposed methods was validated statistically and applied successfully to determination of gemifloxacin mesylate in pharmaceutical formulation. |
| format | Article |
| id | doaj-art-ef2993fbfa434b1f8164dc24532d2ef5 |
| institution | OA Journals |
| issn | 0973-4945 2090-9810 |
| language | English |
| publishDate | 2010-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | E-Journal of Chemistry |
| spelling | doaj-art-ef2993fbfa434b1f8164dc24532d2ef52025-08-20T02:22:25ZengWileyE-Journal of Chemistry0973-49452090-98102010-01-017S1S344S34810.1155/2010/346847Validated UV-Spectrophotometric Methods for Determination of Gemifloxacin Mesylate in Pharmaceutical Tablet Dosage FormsR. Rote Ambadas0P. Pingle Sunita1Department of Pharmaceutical Chemistry, M. G. V.’s Pharmacy College, Panchavati Mumbai - Agra Road, Nashik-422003, Maharashtra, IndiaDepartment of Pharmaceutical Chemistry, M. G. V.’s Pharmacy College, Panchavati Mumbai - Agra Road, Nashik-422003, Maharashtra, IndiaTwo simple, economic and accurate UV spectrophotometric methods have been developed for determination of gemifloxacin mesylate in pharmaceutical tablet formulation. The first UV-spectrophotometric method depends upon the measurement of absorption at the wavelength 263.8 nm. In second area under curve method the wavelength range for detection was selected from 268.5-258.5 nm. Beer’s law was obeyed in the range of 2 to 12 μgmL-1 for both the methods. The proposed methods was validated statistically and applied successfully to determination of gemifloxacin mesylate in pharmaceutical formulation.http://dx.doi.org/10.1155/2010/346847 |
| spellingShingle | R. Rote Ambadas P. Pingle Sunita Validated UV-Spectrophotometric Methods for Determination of Gemifloxacin Mesylate in Pharmaceutical Tablet Dosage Forms E-Journal of Chemistry |
| title | Validated UV-Spectrophotometric Methods for Determination of Gemifloxacin Mesylate in Pharmaceutical Tablet Dosage Forms |
| title_full | Validated UV-Spectrophotometric Methods for Determination of Gemifloxacin Mesylate in Pharmaceutical Tablet Dosage Forms |
| title_fullStr | Validated UV-Spectrophotometric Methods for Determination of Gemifloxacin Mesylate in Pharmaceutical Tablet Dosage Forms |
| title_full_unstemmed | Validated UV-Spectrophotometric Methods for Determination of Gemifloxacin Mesylate in Pharmaceutical Tablet Dosage Forms |
| title_short | Validated UV-Spectrophotometric Methods for Determination of Gemifloxacin Mesylate in Pharmaceutical Tablet Dosage Forms |
| title_sort | validated uv spectrophotometric methods for determination of gemifloxacin mesylate in pharmaceutical tablet dosage forms |
| url | http://dx.doi.org/10.1155/2010/346847 |
| work_keys_str_mv | AT rroteambadas validateduvspectrophotometricmethodsfordeterminationofgemifloxacinmesylateinpharmaceuticaltabletdosageforms AT ppinglesunita validateduvspectrophotometricmethodsfordeterminationofgemifloxacinmesylateinpharmaceuticaltabletdosageforms |