Randomized, Double-masked, Placebo-controlled Clinical Trial on the Effects of Propolis and Chlorhexidine Mouthrinses on Gingivitis
Objective: The aim of this study was to compare the effects of typified propolis and chlorhexidine mouthrinses on gingival health in a randomized double-masked placebo-controlled clinical trial. Methods: Sixty participants were randomized to 3 mouthrinse study groups: 1) 2% typified propolis (n=20...
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| Format: | Article |
| Language: | English |
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Universidade Estadual Paulista
2014-01-01
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| Series: | Brazilian Dental Science |
| Online Access: | https://ojs.ict.unesp.br/index.php/cob/article/view/947 |
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| author | Camilo Anauate-Netto Andréa Anido-Anido Hugo Roberto Lewgoy Ricardo Matsumoto Roberta Caroline Bruschi Alonso Maria Cristina Marcucci Niraldo Paulino Walter Antonio Bretz |
| author_facet | Camilo Anauate-Netto Andréa Anido-Anido Hugo Roberto Lewgoy Ricardo Matsumoto Roberta Caroline Bruschi Alonso Maria Cristina Marcucci Niraldo Paulino Walter Antonio Bretz |
| author_sort | Camilo Anauate-Netto |
| collection | DOAJ |
| description |
Objective: The aim of this study was to compare the effects of typified propolis and chlorhexidine mouthrinses on gingival health in a randomized double-masked placebo-controlled clinical trial.
Methods: Sixty participants were randomized to 3 mouthrinse study groups: 1) 2% typified propolis (n=20); 2) 0.12% chlorhexidine (n=20), and 3) placebo (n=20). Participants rinsed unsupervised twice a day for 28 days. The Papillary Bleeding Score (PBS) was measured on the mesio-buccal surfaces of all teeth at baseline and 28 days thereafter. Co-variance analysis was employed to compare PBS average values and the number of sites with PBS ?2 among study groups. Sub-group analysis was further applied to participants who were <40 years-old.
Results: The results show efficacy of propolis mouthrinse when comparing before and after treatment protocols significantly for a reduction of mean PBS scores. When looking at younger participants after 28 days, propolis mouthrinse was superior to all groups in reducing mean PBS scores and significantly so when compared to 0.12% chlorhexidine mouthrinse.
Conclusion: The efficacy of 2% typified propolis mouthrinse was demonstrated in reducing the levels of gingival inflammation. These results need to be duplicated by other investigators by employing similar study protocols.
Descriptors: Randomized Clinical Trial, Propolis, Chlorhexidine, Gingivitis
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| format | Article |
| id | doaj-art-ef29900dd1894fd3b2b1cb93cde48699 |
| institution | Kabale University |
| issn | 2178-6011 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Universidade Estadual Paulista |
| record_format | Article |
| series | Brazilian Dental Science |
| spelling | doaj-art-ef29900dd1894fd3b2b1cb93cde486992025-08-22T17:55:04ZengUniversidade Estadual PaulistaBrazilian Dental Science2178-60112014-01-0117110.14295/bds.2014.v17i1.947Randomized, Double-masked, Placebo-controlled Clinical Trial on the Effects of Propolis and Chlorhexidine Mouthrinses on GingivitisCamilo Anauate-Netto0Andréa Anido-AnidoHugo Roberto LewgoyRicardo MatsumotoRoberta Caroline Bruschi AlonsoMaria Cristina MarcucciNiraldo PaulinoWalter Antonio BretzBiomaterials Research Group – School of Dentistry – UNIBAN Bandeirante Anhanguera University – São Paulo – SP – Brazil. Objective: The aim of this study was to compare the effects of typified propolis and chlorhexidine mouthrinses on gingival health in a randomized double-masked placebo-controlled clinical trial. Methods: Sixty participants were randomized to 3 mouthrinse study groups: 1) 2% typified propolis (n=20); 2) 0.12% chlorhexidine (n=20), and 3) placebo (n=20). Participants rinsed unsupervised twice a day for 28 days. The Papillary Bleeding Score (PBS) was measured on the mesio-buccal surfaces of all teeth at baseline and 28 days thereafter. Co-variance analysis was employed to compare PBS average values and the number of sites with PBS ?2 among study groups. Sub-group analysis was further applied to participants who were <40 years-old. Results: The results show efficacy of propolis mouthrinse when comparing before and after treatment protocols significantly for a reduction of mean PBS scores. When looking at younger participants after 28 days, propolis mouthrinse was superior to all groups in reducing mean PBS scores and significantly so when compared to 0.12% chlorhexidine mouthrinse. Conclusion: The efficacy of 2% typified propolis mouthrinse was demonstrated in reducing the levels of gingival inflammation. These results need to be duplicated by other investigators by employing similar study protocols. Descriptors: Randomized Clinical Trial, Propolis, Chlorhexidine, Gingivitis https://ojs.ict.unesp.br/index.php/cob/article/view/947 |
| spellingShingle | Camilo Anauate-Netto Andréa Anido-Anido Hugo Roberto Lewgoy Ricardo Matsumoto Roberta Caroline Bruschi Alonso Maria Cristina Marcucci Niraldo Paulino Walter Antonio Bretz Randomized, Double-masked, Placebo-controlled Clinical Trial on the Effects of Propolis and Chlorhexidine Mouthrinses on Gingivitis Brazilian Dental Science |
| title | Randomized, Double-masked, Placebo-controlled Clinical Trial on the Effects of Propolis and Chlorhexidine Mouthrinses on Gingivitis |
| title_full | Randomized, Double-masked, Placebo-controlled Clinical Trial on the Effects of Propolis and Chlorhexidine Mouthrinses on Gingivitis |
| title_fullStr | Randomized, Double-masked, Placebo-controlled Clinical Trial on the Effects of Propolis and Chlorhexidine Mouthrinses on Gingivitis |
| title_full_unstemmed | Randomized, Double-masked, Placebo-controlled Clinical Trial on the Effects of Propolis and Chlorhexidine Mouthrinses on Gingivitis |
| title_short | Randomized, Double-masked, Placebo-controlled Clinical Trial on the Effects of Propolis and Chlorhexidine Mouthrinses on Gingivitis |
| title_sort | randomized double masked placebo controlled clinical trial on the effects of propolis and chlorhexidine mouthrinses on gingivitis |
| url | https://ojs.ict.unesp.br/index.php/cob/article/view/947 |
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