Integrated transcriptomics and metabolomics studies reveal the therapeutic effects of Astragalus polysaccharides on cancer cachexia muscle atrophy
Abstract Cancer cachexia (CC) is a condition causing significant muscle loss in advanced cancer patients, severely impacting their quality of life and life expectancy. The autophagy–lysosome system is a key pathway in muscle depletion in CC, but targeted therapies are lacking. This study investigate...
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| Main Authors: | Zhihan Tian, Yong Wang, Xue Liu, Xin Xin, Shuai Liu, Yiwei Qu, Ziyuan Li, Xiaoyu Su, Dufang Ma |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-07-01
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| Series: | Scientific Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/s41598-025-11342-x |
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