Problems of selecting an anticoagulant for secondary stroke prevention in patients with atrial fibrillation
The article describes the urgent problem of ischemic stroke prevention in patients with atrial fibrillation. It is proved that ischemic stroke in combination with AF is the most severe in terms of developing stable motor and speech disorders and disability. The frail older patients, as well as patie...
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| Format: | Article |
| Language: | Russian |
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«SILICEA-POLIGRAF» LLC
2021-10-01
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| Series: | Кардиоваскулярная терапия и профилактика |
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| Online Access: | https://cardiovascular.elpub.ru/jour/article/view/3044 |
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| author | V. V. Gusev O. A. Lvova N. A. Shamalov |
| author_facet | V. V. Gusev O. A. Lvova N. A. Shamalov |
| author_sort | V. V. Gusev |
| collection | DOAJ |
| description | The article describes the urgent problem of ischemic stroke prevention in patients with atrial fibrillation. It is proved that ischemic stroke in combination with AF is the most severe in terms of developing stable motor and speech disorders and disability. The frail older patients, as well as patients with swallowing disorders and reduced medical adherence present a special problem from this point of view. The most famous clinical studies on secondary prevention of cardioembolic stroke are RE-LY, ROCKET-AF, and ARISTOTLE. Based on subanalyses of randomized controlled trials, direct oral anticoagulants demonstrated a favorable efficacy profile in patients with atrial fibrillation and stroke/ transient ischemic attack, but the level of knowledge on each of them remained different. A number of advantages of rivaroxaban for primary and secondary prevention of stroke in patients with atrial fibrillation, including the elderly and patients with cognitive impairments and swallowing disorders, have been demonstrated. |
| format | Article |
| id | doaj-art-ef1c952bb69d451e939362d0a8b07586 |
| institution | Kabale University |
| issn | 1728-8800 2619-0125 |
| language | Russian |
| publishDate | 2021-10-01 |
| publisher | «SILICEA-POLIGRAF» LLC |
| record_format | Article |
| series | Кардиоваскулярная терапия и профилактика |
| spelling | doaj-art-ef1c952bb69d451e939362d0a8b075862025-08-20T03:57:17Zrus«SILICEA-POLIGRAF» LLCКардиоваскулярная терапия и профилактика1728-88002619-01252021-10-0120610.15829/1728-8800-2021-30442340Problems of selecting an anticoagulant for secondary stroke prevention in patients with atrial fibrillationV. V. Gusev0O. A. Lvova1N. A. Shamalov2Central City Clinical Hospital № 23; Ural Federal University named after the First President of Russia B.N. Yeltsin; Ural State Medical UniversityUral Federal University named after the First President of Russia B.N. Yeltsin; Ural State Medical UniversityInstitute of Cerebrovascular Pathology and Stroke, Federal Center of Brain Research and NeurotechnologiesThe article describes the urgent problem of ischemic stroke prevention in patients with atrial fibrillation. It is proved that ischemic stroke in combination with AF is the most severe in terms of developing stable motor and speech disorders and disability. The frail older patients, as well as patients with swallowing disorders and reduced medical adherence present a special problem from this point of view. The most famous clinical studies on secondary prevention of cardioembolic stroke are RE-LY, ROCKET-AF, and ARISTOTLE. Based on subanalyses of randomized controlled trials, direct oral anticoagulants demonstrated a favorable efficacy profile in patients with atrial fibrillation and stroke/ transient ischemic attack, but the level of knowledge on each of them remained different. A number of advantages of rivaroxaban for primary and secondary prevention of stroke in patients with atrial fibrillation, including the elderly and patients with cognitive impairments and swallowing disorders, have been demonstrated.https://cardiovascular.elpub.ru/jour/article/view/3044ischemic strokeatrial fibrillationsecondary preventiondirect oral anticoagulants |
| spellingShingle | V. V. Gusev O. A. Lvova N. A. Shamalov Problems of selecting an anticoagulant for secondary stroke prevention in patients with atrial fibrillation Кардиоваскулярная терапия и профилактика ischemic stroke atrial fibrillation secondary prevention direct oral anticoagulants |
| title | Problems of selecting an anticoagulant for secondary stroke prevention in patients with atrial fibrillation |
| title_full | Problems of selecting an anticoagulant for secondary stroke prevention in patients with atrial fibrillation |
| title_fullStr | Problems of selecting an anticoagulant for secondary stroke prevention in patients with atrial fibrillation |
| title_full_unstemmed | Problems of selecting an anticoagulant for secondary stroke prevention in patients with atrial fibrillation |
| title_short | Problems of selecting an anticoagulant for secondary stroke prevention in patients with atrial fibrillation |
| title_sort | problems of selecting an anticoagulant for secondary stroke prevention in patients with atrial fibrillation |
| topic | ischemic stroke atrial fibrillation secondary prevention direct oral anticoagulants |
| url | https://cardiovascular.elpub.ru/jour/article/view/3044 |
| work_keys_str_mv | AT vvgusev problemsofselectingananticoagulantforsecondarystrokepreventioninpatientswithatrialfibrillation AT oalvova problemsofselectingananticoagulantforsecondarystrokepreventioninpatientswithatrialfibrillation AT nashamalov problemsofselectingananticoagulantforsecondarystrokepreventioninpatientswithatrialfibrillation |