Recent advances on the impact of protumorigenic dietary‐derived bacterial metabolites on the intestinal stem cell

Abstract The links between diet, microbiome, immunity, and colorectal cancer are well established. The metabolite output of the microbiome, which has a large influence over host health and disease, is related to the composition of the diet. These metabolites subsequently impact on immune and intesti...

Full description

Saved in:
Bibliographic Details
Main Authors: Carys Holmes, Charlotte H. Illingworth, Lee Parry
Format: Article
Language:English
Published: Wiley 2024-12-01
Series:eFood
Subjects:
Online Access:https://doi.org/10.1002/efd2.70023
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1850249694975885312
author Carys Holmes
Charlotte H. Illingworth
Lee Parry
author_facet Carys Holmes
Charlotte H. Illingworth
Lee Parry
author_sort Carys Holmes
collection DOAJ
description Abstract The links between diet, microbiome, immunity, and colorectal cancer are well established. The metabolite output of the microbiome, which has a large influence over host health and disease, is related to the composition of the diet. These metabolites subsequently impact on immune and intestinal epithelial either directly or indirectly via production of secondary metabolites. Here we summarize the latest findings and briefly discuss their potential for managing disease risk.
format Article
id doaj-art-ef1772a11ccd4493b14fa51ec798f2e7
institution OA Journals
issn 2666-3066
language English
publishDate 2024-12-01
publisher Wiley
record_format Article
series eFood
spelling doaj-art-ef1772a11ccd4493b14fa51ec798f2e72025-08-20T01:58:27ZengWileyeFood2666-30662024-12-0156n/an/a10.1002/efd2.70023Recent advances on the impact of protumorigenic dietary‐derived bacterial metabolites on the intestinal stem cellCarys Holmes0Charlotte H. Illingworth1Lee Parry2School of Biosciences, European Cancer Stem Cell Research Institute Cardiff University Cardiff UKSchool of Biosciences, European Cancer Stem Cell Research Institute Cardiff University Cardiff UKSchool of Biosciences, European Cancer Stem Cell Research Institute Cardiff University Cardiff UKAbstract The links between diet, microbiome, immunity, and colorectal cancer are well established. The metabolite output of the microbiome, which has a large influence over host health and disease, is related to the composition of the diet. These metabolites subsequently impact on immune and intestinal epithelial either directly or indirectly via production of secondary metabolites. Here we summarize the latest findings and briefly discuss their potential for managing disease risk.https://doi.org/10.1002/efd2.70023colorectal cancerdietintestinal stem cellmicrobiomesecondary metabolites
spellingShingle Carys Holmes
Charlotte H. Illingworth
Lee Parry
Recent advances on the impact of protumorigenic dietary‐derived bacterial metabolites on the intestinal stem cell
eFood
colorectal cancer
diet
intestinal stem cell
microbiome
secondary metabolites
title Recent advances on the impact of protumorigenic dietary‐derived bacterial metabolites on the intestinal stem cell
title_full Recent advances on the impact of protumorigenic dietary‐derived bacterial metabolites on the intestinal stem cell
title_fullStr Recent advances on the impact of protumorigenic dietary‐derived bacterial metabolites on the intestinal stem cell
title_full_unstemmed Recent advances on the impact of protumorigenic dietary‐derived bacterial metabolites on the intestinal stem cell
title_short Recent advances on the impact of protumorigenic dietary‐derived bacterial metabolites on the intestinal stem cell
title_sort recent advances on the impact of protumorigenic dietary derived bacterial metabolites on the intestinal stem cell
topic colorectal cancer
diet
intestinal stem cell
microbiome
secondary metabolites
url https://doi.org/10.1002/efd2.70023
work_keys_str_mv AT carysholmes recentadvancesontheimpactofprotumorigenicdietaryderivedbacterialmetabolitesontheintestinalstemcell
AT charlottehillingworth recentadvancesontheimpactofprotumorigenicdietaryderivedbacterialmetabolitesontheintestinalstemcell
AT leeparry recentadvancesontheimpactofprotumorigenicdietaryderivedbacterialmetabolitesontheintestinalstemcell