The clinic application of mNGS and ENA-78 assays to identify intra-amniotic infection/inflammation

The clinic application of mNGS and ENA-78 assays to identify intra-amniotic infection/inflammation

ObjectiveThe objective of this study is to explore whether metagenomic next-generation sequencing (mNGS) and Epithelial Neutrophil Activating Peptide-78 (ENA-78) assays in the amniotic fluid (AF) of patients with preterm labor (PTL) could be employed for diagnosing intra-amniotic infection/inflammat...

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Bibliographic Details
Main Authors: Di Shen, Hui Ju, Hongying Wang, Xietong Wang, Guangzhen Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
preterm labor
intra-amniotic infection/inflammation
metagenomic next-generation sequencing
neutrophil extracellular traps
cervical insufficiency
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2025.1510671/full
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