Evaluation of methicillin-resistant Staphylococcus aureus nasal carriage in Malagasy patients
Introduction: Methicillin-resistant Staphylococcus aureus (MRSA) is an important cause of infections. It is well recognized that nasal carriage of S. aureus represents a potent and increasingly prevalent risk factor for subsequent S. aureus infection. However, in Madagascar no data exist concerning...
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The Journal of Infection in Developing Countries
2013-04-01
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| Series: | Journal of Infection in Developing Countries |
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| Online Access: | https://jidc.org/index.php/journal/article/view/2460 |
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| author | Tsiry Rasamiravaka Saida Rasoanandrasana Norosoa Julie Julie Zafindraibe Aimee Olivat Rakoto Alson Andry Rasamindrakotroka |
| author_facet | Tsiry Rasamiravaka Saida Rasoanandrasana Norosoa Julie Julie Zafindraibe Aimee Olivat Rakoto Alson Andry Rasamindrakotroka |
| author_sort | Tsiry Rasamiravaka |
| collection | DOAJ |
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Introduction: Methicillin-resistant Staphylococcus aureus (MRSA) is an important cause of infections. It is well recognized that nasal carriage of S. aureus represents a potent and increasingly prevalent risk factor for subsequent S. aureus infection. However, in Madagascar no data exist concerning this nasal carriage of S. aureus.
Methodology: Nasal swabs from 304 different patients attending the Laboratory of Training and Research in Medical Biology of Madagascar were cultured for methicillin sensitive (MSSA) and MRSA.
Results: One hundred and sixteen patients had S. aureus in their noses (38.16 ± 5.46%) of whom 45 (14.80 ± 3.99%) had MRSA. A risk factor for MSSA nasal carriage included a history of hospitalization when antibiotics were administered (odds ratio [OR] 2.25, 1.09 - 4.64). Among MRSA nasal isolates, high rate of resistance to other antibiotics was observed, particularly for trimethoprim-sulfamethoxazole (68.89%), erythromycin (66.67%) and ofloxacin (53.33%).
Conclusion: Our data showed a high rate of MRSA nasal carriage and a high rate of multidrug resistance. A strategic policy against the spread of multidrug resistant strains is desirable.
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| format | Article |
| id | doaj-art-ef05ec99767c489e923a0f7223c2a889 |
| institution | OA Journals |
| issn | 1972-2680 |
| language | English |
| publishDate | 2013-04-01 |
| publisher | The Journal of Infection in Developing Countries |
| record_format | Article |
| series | Journal of Infection in Developing Countries |
| spelling | doaj-art-ef05ec99767c489e923a0f7223c2a8892025-08-20T02:27:15ZengThe Journal of Infection in Developing CountriesJournal of Infection in Developing Countries1972-26802013-04-0170410.3855/jidc.2460Evaluation of methicillin-resistant Staphylococcus aureus nasal carriage in Malagasy patientsTsiry Rasamiravaka0Saida Rasoanandrasana1Norosoa Julie Julie Zafindraibe2Aimee Olivat Rakoto Alson3Andry Rasamindrakotroka4Faculty of Medicine, University of Antananarivo, Antananarivo, MadagascarFaculty of Medicine, University of Antananarivo, Antananarivo, MadagascarFaculty of Medicine, University of Antananarivo, Antananarivo, MadagascarFaculty of Medicine, University of Antananarivo, Antananarivo, MadagascarFaculty of Medicine, University of Antananarivo, Antananarivo, Madagascar Introduction: Methicillin-resistant Staphylococcus aureus (MRSA) is an important cause of infections. It is well recognized that nasal carriage of S. aureus represents a potent and increasingly prevalent risk factor for subsequent S. aureus infection. However, in Madagascar no data exist concerning this nasal carriage of S. aureus. Methodology: Nasal swabs from 304 different patients attending the Laboratory of Training and Research in Medical Biology of Madagascar were cultured for methicillin sensitive (MSSA) and MRSA. Results: One hundred and sixteen patients had S. aureus in their noses (38.16 ± 5.46%) of whom 45 (14.80 ± 3.99%) had MRSA. A risk factor for MSSA nasal carriage included a history of hospitalization when antibiotics were administered (odds ratio [OR] 2.25, 1.09 - 4.64). Among MRSA nasal isolates, high rate of resistance to other antibiotics was observed, particularly for trimethoprim-sulfamethoxazole (68.89%), erythromycin (66.67%) and ofloxacin (53.33%). Conclusion: Our data showed a high rate of MRSA nasal carriage and a high rate of multidrug resistance. A strategic policy against the spread of multidrug resistant strains is desirable. https://jidc.org/index.php/journal/article/view/2460MRSAMalagasy labnasal carriagerisk factors |
| spellingShingle | Tsiry Rasamiravaka Saida Rasoanandrasana Norosoa Julie Julie Zafindraibe Aimee Olivat Rakoto Alson Andry Rasamindrakotroka Evaluation of methicillin-resistant Staphylococcus aureus nasal carriage in Malagasy patients Journal of Infection in Developing Countries MRSA Malagasy lab nasal carriage risk factors |
| title | Evaluation of methicillin-resistant Staphylococcus aureus nasal carriage in Malagasy patients |
| title_full | Evaluation of methicillin-resistant Staphylococcus aureus nasal carriage in Malagasy patients |
| title_fullStr | Evaluation of methicillin-resistant Staphylococcus aureus nasal carriage in Malagasy patients |
| title_full_unstemmed | Evaluation of methicillin-resistant Staphylococcus aureus nasal carriage in Malagasy patients |
| title_short | Evaluation of methicillin-resistant Staphylococcus aureus nasal carriage in Malagasy patients |
| title_sort | evaluation of methicillin resistant staphylococcus aureus nasal carriage in malagasy patients |
| topic | MRSA Malagasy lab nasal carriage risk factors |
| url | https://jidc.org/index.php/journal/article/view/2460 |
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