Lithium Induced Amenorrhea: A First Case Report
A 19-year-old female, known case of bipolar disorder had history of amenorrhea (absence of menstruation) for three years. While other causes of amenorrhea such as CNS, pregnancy, other medications, and thyroid issues were ruled out, she was found to have hyper-prolactinemia. Although antipsychotic...
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| Format: | Article |
| Language: | English |
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Vilnius University Press
2024-02-01
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| Series: | Acta Medica Lituanica |
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| Online Access: | https://www.zurnalai.vu.lt/AML/article/view/33279 |
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| author | Balakumar KE Vandana Tayal Vidhya Egambarame Vandana Roy |
| author_facet | Balakumar KE Vandana Tayal Vidhya Egambarame Vandana Roy |
| author_sort | Balakumar KE |
| collection | DOAJ |
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A 19-year-old female, known case of bipolar disorder had history of amenorrhea (absence of menstruation) for three years. While other causes of amenorrhea such as CNS, pregnancy, other medications, and thyroid issues were ruled out, she was found to have hyper-prolactinemia. Although antipsychotic medications are known to cause amenorrhea due to dopamine receptor blockade, which may result in hyperprolactinemia, the patient’s symptoms began before she started these medications. Only drug that she was on for long period is lithium. Current literature shows mixed evidence about lithium’s impact on prolactin levels, which can affect menstruation. This case may represent the first report of lithium causing amenorrhea through elevated prolactin levels. Clinicians should be aware of this potential side effect and monitor patients accordingly. Further studies are needed to confirm and understand this potential link.
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| format | Article |
| id | doaj-art-ef0522d10bcc491f9b5464ac3e360b4f |
| institution | Kabale University |
| issn | 1392-0138 2029-4174 |
| language | English |
| publishDate | 2024-02-01 |
| publisher | Vilnius University Press |
| record_format | Article |
| series | Acta Medica Lituanica |
| spelling | doaj-art-ef0522d10bcc491f9b5464ac3e360b4f2025-02-11T18:08:39ZengVilnius University PressActa Medica Lituanica1392-01382029-41742024-02-0131110.15388/Amed.2024.31.1.5Lithium Induced Amenorrhea: A First Case ReportBalakumar KE0Vandana Tayal1Vidhya Egambarame2Vandana Roy3Maulana Azad Medical College, IndiaMaulana Azad Medical College, IndiaMaulana Azad Medical College, IndiaMaulana Azad Medical College, India A 19-year-old female, known case of bipolar disorder had history of amenorrhea (absence of menstruation) for three years. While other causes of amenorrhea such as CNS, pregnancy, other medications, and thyroid issues were ruled out, she was found to have hyper-prolactinemia. Although antipsychotic medications are known to cause amenorrhea due to dopamine receptor blockade, which may result in hyperprolactinemia, the patient’s symptoms began before she started these medications. Only drug that she was on for long period is lithium. Current literature shows mixed evidence about lithium’s impact on prolactin levels, which can affect menstruation. This case may represent the first report of lithium causing amenorrhea through elevated prolactin levels. Clinicians should be aware of this potential side effect and monitor patients accordingly. Further studies are needed to confirm and understand this potential link. https://www.zurnalai.vu.lt/AML/article/view/33279female healthlithium psychiatry |
| spellingShingle | Balakumar KE Vandana Tayal Vidhya Egambarame Vandana Roy Lithium Induced Amenorrhea: A First Case Report Acta Medica Lituanica female health lithium psychiatry |
| title | Lithium Induced Amenorrhea: A First Case Report |
| title_full | Lithium Induced Amenorrhea: A First Case Report |
| title_fullStr | Lithium Induced Amenorrhea: A First Case Report |
| title_full_unstemmed | Lithium Induced Amenorrhea: A First Case Report |
| title_short | Lithium Induced Amenorrhea: A First Case Report |
| title_sort | lithium induced amenorrhea a first case report |
| topic | female health lithium psychiatry |
| url | https://www.zurnalai.vu.lt/AML/article/view/33279 |
| work_keys_str_mv | AT balakumarke lithiuminducedamenorrheaafirstcasereport AT vandanatayal lithiuminducedamenorrheaafirstcasereport AT vidhyaegambarame lithiuminducedamenorrheaafirstcasereport AT vandanaroy lithiuminducedamenorrheaafirstcasereport |