Distinct Molecular Epidemiology, Transmission Patterns, and Resistance Mutations of HIV-1 Subtypes A1, A6, and A7 in Bulgaria

Distinct Molecular Epidemiology, Transmission Patterns, and Resistance Mutations of HIV-1 Subtypes A1, A6, and A7 in Bulgaria

By 2022, Bulgaria’s National Reference Laboratory had confirmed 4024 HIV cases. We analyzed 132 pol gene sequences to characterize the molecular epidemiology of HIV-1 subtypes A1, A6, and A7 (2001–2022). A1 accounted for 50.0% (66/132) of cases, increasing after 2014, with peaks in 2019 and 2022. A6...

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Main Authors: Aleksandra Partsuneva, Anna Gancheva, Reneta Dimitrova, Lyubomira Grigorova, Asya Kostadinova, Maria Nikolova, Radoslava Emilova, Nina Yancheva, Rusina Grozdeva, Ivailo Alexiev
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Microorganisms
Subjects:
HIV-1
subtype A1
subtype A6
subtype A7
molecular epidemiology
phylogenetic analysis
Online Access:https://www.mdpi.com/2076-2607/13/5/1108
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