MCM-41-Accelerated PWA Catalysis of Friedel-Crafts Reaction of Indoles and Isatins

Ordered mesoporous siliceous material has been identified as one of the key elements of the catalysis concept. Here we report an efficient Friedel-Crafts reaction of indoles with isatins catalyzed by PWA/MCM-41, which got the di(indolyl)indolin-2-ones derivatives with high yield. Moreover, the catal...

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Bibliographic Details
Main Authors: Liuzhuang Xing, YongHai Hui, Jinghui Yang, Xuejian Xing, Yadong Hou, Yang Wu, Kui Fan, Wei Wang
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Journal of Chemistry
Online Access:http://dx.doi.org/10.1155/2018/2785067
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Summary:Ordered mesoporous siliceous material has been identified as one of the key elements of the catalysis concept. Here we report an efficient Friedel-Crafts reaction of indoles with isatins catalyzed by PWA/MCM-41, which got the di(indolyl)indolin-2-ones derivatives with high yield. Moreover, the catalysts were characterized by XRD and SEM/EDS, the EDS spectrum indicated that the catalyst used in this reaction also contains tungsten, and the proposed mechanism for the synthesis of 3,3-di(indolyl)indolin-2-ones was also discussed. Finally, the catalyst can be reused repeatedly for several times without obvious loss of activity.
ISSN:2090-9063
2090-9071