Multiple Sclerosis – An Ophthalmologist’s perspective

Multiple sclerosis is a nervous system disease that affects brain and spinal cord. It damages the myelin sheath, the material that surrounds and protects the nerve cells. Its symptoms are varied and unpredictable. It commonly affects the optic nerve and ocular movements. Up to 50% of patients with m...

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Main Authors: Reena Sharma, Rohit Saxena, Rohit Bhatia, Vimla Menon
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2013-04-01
Series:Delhi Journal of Ophthalmology
Subjects:
Online Access:https://journals.lww.com/10.7869/djo.2012.79
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author Reena Sharma
Rohit Saxena
Rohit Bhatia
Vimla Menon
author_facet Reena Sharma
Rohit Saxena
Rohit Bhatia
Vimla Menon
author_sort Reena Sharma
collection DOAJ
description Multiple sclerosis is a nervous system disease that affects brain and spinal cord. It damages the myelin sheath, the material that surrounds and protects the nerve cells. Its symptoms are varied and unpredictable. It commonly affects the optic nerve and ocular movements. Up to 50% of patients with multiple sclerosis will develop an episode of optic neuritis, and 20-30% of the time optic neuritis is the presenting sign of multiple sclerosis. Optic neuritis is diagnosed clinically and followed up using visual acuity, colour vision, contrast sensitivity, visual fields, magnetic resonance imaging and optical coherence tomography. Bilateral internuclear ophthalmoplegia, abnormalities resulting from cerebellar damage or to its connections and pendular nystagmus are other common ophthalmic manifestations of the disease. Multiple sclerosis is diagnosed using McDonald criterion, based on the occurrence of at least two clinical episodes of neurological involvement separated in time and space. The magnetic resonance imaging aids the diagnosis and requires the presence of lesions in at least 2 of the four locations-periventricular, juxtacortical, infratentorial and spinal cord. The treatment of multiple sclerosis is multidisciplinary, invoving the treating physician, physiotherapists, occupational therapists, nurses and social workers. There are no drugs to cure multiple sclerosis, but several therapies are available that can ameliorate the symptoms of multiple sclerosis and, in some cases, slow the disease progression.
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spelling doaj-art-eef7f381dfb740779c0ae2f596b8ed462025-08-20T01:48:33ZengWolters Kluwer Medknow PublicationsDelhi Journal of Ophthalmology0972-02002454-27842013-04-0123425125610.7869/djo.2012.79Multiple Sclerosis – An Ophthalmologist’s perspectiveReena SharmaRohit SaxenaRohit BhatiaVimla MenonMultiple sclerosis is a nervous system disease that affects brain and spinal cord. It damages the myelin sheath, the material that surrounds and protects the nerve cells. Its symptoms are varied and unpredictable. It commonly affects the optic nerve and ocular movements. Up to 50% of patients with multiple sclerosis will develop an episode of optic neuritis, and 20-30% of the time optic neuritis is the presenting sign of multiple sclerosis. Optic neuritis is diagnosed clinically and followed up using visual acuity, colour vision, contrast sensitivity, visual fields, magnetic resonance imaging and optical coherence tomography. Bilateral internuclear ophthalmoplegia, abnormalities resulting from cerebellar damage or to its connections and pendular nystagmus are other common ophthalmic manifestations of the disease. Multiple sclerosis is diagnosed using McDonald criterion, based on the occurrence of at least two clinical episodes of neurological involvement separated in time and space. The magnetic resonance imaging aids the diagnosis and requires the presence of lesions in at least 2 of the four locations-periventricular, juxtacortical, infratentorial and spinal cord. The treatment of multiple sclerosis is multidisciplinary, invoving the treating physician, physiotherapists, occupational therapists, nurses and social workers. There are no drugs to cure multiple sclerosis, but several therapies are available that can ameliorate the symptoms of multiple sclerosis and, in some cases, slow the disease progression.https://journals.lww.com/10.7869/djo.2012.79optic neuritismyelin sheathinternuclear ophthalmoplegia
spellingShingle Reena Sharma
Rohit Saxena
Rohit Bhatia
Vimla Menon
Multiple Sclerosis – An Ophthalmologist’s perspective
Delhi Journal of Ophthalmology
optic neuritis
myelin sheath
internuclear ophthalmoplegia
title Multiple Sclerosis – An Ophthalmologist’s perspective
title_full Multiple Sclerosis – An Ophthalmologist’s perspective
title_fullStr Multiple Sclerosis – An Ophthalmologist’s perspective
title_full_unstemmed Multiple Sclerosis – An Ophthalmologist’s perspective
title_short Multiple Sclerosis – An Ophthalmologist’s perspective
title_sort multiple sclerosis an ophthalmologist s perspective
topic optic neuritis
myelin sheath
internuclear ophthalmoplegia
url https://journals.lww.com/10.7869/djo.2012.79
work_keys_str_mv AT reenasharma multiplesclerosisanophthalmologistsperspective
AT rohitsaxena multiplesclerosisanophthalmologistsperspective
AT rohitbhatia multiplesclerosisanophthalmologistsperspective
AT vimlamenon multiplesclerosisanophthalmologistsperspective