The impact of acute morning versus evening high-intensity interval training on circulating irisin levels and metabolic parameters in overweight postmenopausal women
Purpose of the research: Exercise is considered beneficial for postmenopausal women to manage weight and improve metabolism, but research on the impact of exercise timing on irisin levels and metabolic health in overweight postmenopausal women is inconclusive. This study aims to compare the effects...
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| Language: | English |
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Elsevier
2025-09-01
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| Series: | Experimental Gerontology |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S0531556525001500 |
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| author | Akram Jafari Fariba Kazemi |
| author_facet | Akram Jafari Fariba Kazemi |
| author_sort | Akram Jafari |
| collection | DOAJ |
| description | Purpose of the research: Exercise is considered beneficial for postmenopausal women to manage weight and improve metabolism, but research on the impact of exercise timing on irisin levels and metabolic health in overweight postmenopausal women is inconclusive. This study aims to compare the effects of acute morning and evening high-intensity interval training (HIIT) on irisin levels and metabolic parameters in overweight postmenopausal women. Methods: Fifty-two overweight postmenopausal women aged 53.91 ± 2.71 years were randomly assigned to HIIT (n = 28) and control (n = 24) groups. The HIIT group performed 20 min of repeated 8-second cycling sprints interspersed with 12-second rest intervals at 08:00 and 18:00, with at least 36 h of recovery between sessions, in a randomized order. Blood samples were collected 5 min before, and 5 and 120 min after exercise. Result: Significant within-group increases in irisin (p < 0.01), insulin (p < 0.01), and glucose (p < 0.05) were observed following HIIT. A main effect of time of day revealed higher irisin concentrations in the evening (p < 0.01), although no significant interaction was found between exercise timing and group. No between-group differences in area under the curve (AUC) for irisin or insulin were detected. Conclusions: Acute HIIT elicited favorable changes in irisin and metabolic markers regardless of time of day. Irisin levels increased significantly after HIIT in both morning and evening sessions, with higher baseline concentrations observed in the evening, suggesting a potential circadian influence on irisin secretion. |
| format | Article |
| id | doaj-art-eef08db91bfe455ebb0e01b534e09684 |
| institution | DOAJ |
| issn | 1873-6815 |
| language | English |
| publishDate | 2025-09-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Experimental Gerontology |
| spelling | doaj-art-eef08db91bfe455ebb0e01b534e096842025-08-20T02:44:52ZengElsevierExperimental Gerontology1873-68152025-09-0120811282110.1016/j.exger.2025.112821The impact of acute morning versus evening high-intensity interval training on circulating irisin levels and metabolic parameters in overweight postmenopausal womenAkram Jafari0Fariba Kazemi1Corresponding author at: Physical Education Department, Islamic Azad University, Shahrekord Branch, Shahrekord, Iran.; Department of Physical Education and Sport Sciences, ShK.C., Islamic Azad University, Shahrekord, IranDepartment of Physical Education and Sport Sciences, ShK.C., Islamic Azad University, Shahrekord, IranPurpose of the research: Exercise is considered beneficial for postmenopausal women to manage weight and improve metabolism, but research on the impact of exercise timing on irisin levels and metabolic health in overweight postmenopausal women is inconclusive. This study aims to compare the effects of acute morning and evening high-intensity interval training (HIIT) on irisin levels and metabolic parameters in overweight postmenopausal women. Methods: Fifty-two overweight postmenopausal women aged 53.91 ± 2.71 years were randomly assigned to HIIT (n = 28) and control (n = 24) groups. The HIIT group performed 20 min of repeated 8-second cycling sprints interspersed with 12-second rest intervals at 08:00 and 18:00, with at least 36 h of recovery between sessions, in a randomized order. Blood samples were collected 5 min before, and 5 and 120 min after exercise. Result: Significant within-group increases in irisin (p < 0.01), insulin (p < 0.01), and glucose (p < 0.05) were observed following HIIT. A main effect of time of day revealed higher irisin concentrations in the evening (p < 0.01), although no significant interaction was found between exercise timing and group. No between-group differences in area under the curve (AUC) for irisin or insulin were detected. Conclusions: Acute HIIT elicited favorable changes in irisin and metabolic markers regardless of time of day. Irisin levels increased significantly after HIIT in both morning and evening sessions, with higher baseline concentrations observed in the evening, suggesting a potential circadian influence on irisin secretion.http://www.sciencedirect.com/science/article/pii/S0531556525001500ObesityExercisePostmenopausal womenEndocrineMyokine |
| spellingShingle | Akram Jafari Fariba Kazemi The impact of acute morning versus evening high-intensity interval training on circulating irisin levels and metabolic parameters in overweight postmenopausal women Experimental Gerontology Obesity Exercise Postmenopausal women Endocrine Myokine |
| title | The impact of acute morning versus evening high-intensity interval training on circulating irisin levels and metabolic parameters in overweight postmenopausal women |
| title_full | The impact of acute morning versus evening high-intensity interval training on circulating irisin levels and metabolic parameters in overweight postmenopausal women |
| title_fullStr | The impact of acute morning versus evening high-intensity interval training on circulating irisin levels and metabolic parameters in overweight postmenopausal women |
| title_full_unstemmed | The impact of acute morning versus evening high-intensity interval training on circulating irisin levels and metabolic parameters in overweight postmenopausal women |
| title_short | The impact of acute morning versus evening high-intensity interval training on circulating irisin levels and metabolic parameters in overweight postmenopausal women |
| title_sort | impact of acute morning versus evening high intensity interval training on circulating irisin levels and metabolic parameters in overweight postmenopausal women |
| topic | Obesity Exercise Postmenopausal women Endocrine Myokine |
| url | http://www.sciencedirect.com/science/article/pii/S0531556525001500 |
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