Effectiveness and Safety of Contrast Cryolipolysis for Subcutaneous-Fat Reduction

Cryolipolysis is the noninvasive treatment of localized fat through cold-induced panniculitis. The purpose of the present study was to evaluate the safety and efficacy of contrast cryolipolysis for subcutaneous-fat reduction. Contrast cryolipolysis mixes the principles of conventional cryolipolysis...

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Main Authors: Marília Bueno Savacini, Débora Tazinaffo Bueno, Ana Carolina Souza Molina, Ana Caroline Almeida Lopes, Caroline Nogueira Silva, Renata Gomes Moreira, Stephani Almeida, Renata Michelini Guidi, Estela Sant’Ana, Richard Eloin Liebano
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Dermatology Research and Practice
Online Access:http://dx.doi.org/10.1155/2018/5276528
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author Marília Bueno Savacini
Débora Tazinaffo Bueno
Ana Carolina Souza Molina
Ana Caroline Almeida Lopes
Caroline Nogueira Silva
Renata Gomes Moreira
Stephani Almeida
Renata Michelini Guidi
Estela Sant’Ana
Richard Eloin Liebano
author_facet Marília Bueno Savacini
Débora Tazinaffo Bueno
Ana Carolina Souza Molina
Ana Caroline Almeida Lopes
Caroline Nogueira Silva
Renata Gomes Moreira
Stephani Almeida
Renata Michelini Guidi
Estela Sant’Ana
Richard Eloin Liebano
author_sort Marília Bueno Savacini
collection DOAJ
description Cryolipolysis is the noninvasive treatment of localized fat through cold-induced panniculitis. The purpose of the present study was to evaluate the safety and efficacy of contrast cryolipolysis for subcutaneous-fat reduction. Contrast cryolipolysis mixes the principles of conventional cryolipolysis and periods of heating in accordance with the contrast lipocryolysis process. Twenty-one subjects aged 34 ± 9 years were treated with contrast cryolipolysis in the regions of abdomen and flanks through the Polarys® device. Anthropometry, standardized photographs, measurements with a skinfold caliper, and diagnostic ultrasounds were performed at the baseline and during follow-ups at 30, 60, and 90 days after the treatment. The safety assessments included laboratory testing and monitoring of the adverse events. The level of significance for all tests was set at P < 0.05. No significant differences in weight and body mass index were found. The waist measurements at the baseline and 30-day follow-up had significant differences, as did the measurements at the 30-day and 60-day follow-ups. The skinfold and ultrasound measurements were significantly reduced in the treated areas in all the time points compared to the baseline. The laboratory results showed no significant changes from baseline. Temporary adverse effects were resolved spontaneously. This study confirmed that contrast cryolipolysis is safe and effective in reducing the fat layer and improving body contouring.
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spelling doaj-art-eeea72fdd461480a983e074b32c6d3b72025-08-20T03:21:15ZengWileyDermatology Research and Practice1687-61051687-61132018-01-01201810.1155/2018/52765285276528Effectiveness and Safety of Contrast Cryolipolysis for Subcutaneous-Fat ReductionMarília Bueno Savacini0Débora Tazinaffo Bueno1Ana Carolina Souza Molina2Ana Caroline Almeida Lopes3Caroline Nogueira Silva4Renata Gomes Moreira5Stephani Almeida6Renata Michelini Guidi7Estela Sant’Ana8Richard Eloin Liebano9Ibramed Center for Education and Advanced Training (CEFAI), Amparo, BrazilIbramed Center for Education and Advanced Training (CEFAI), Amparo, BrazilIbramed Center for Education and Advanced Training (CEFAI), Amparo, BrazilIbramed Center for Education and Advanced Training (CEFAI), Amparo, BrazilClinical Laboratory of the Ibramed Center for Education and Advanced Training (CEFAI), Amparo, BrazilClinical Laboratory of the Ibramed Center for Education and Advanced Training (CEFAI), Amparo, BrazilClinical Laboratory of the Ibramed Center for Education and Advanced Training (CEFAI), Amparo, BrazilClinical Laboratory of the Ibramed Center for Education and Advanced Training (CEFAI), Amparo, BrazilClinical Laboratory of the Ibramed Center for Education and Advanced Training (CEFAI), Amparo, BrazilDepartment of Physiotherapy, Federal University of São Carlos, São Carlos, BrazilCryolipolysis is the noninvasive treatment of localized fat through cold-induced panniculitis. The purpose of the present study was to evaluate the safety and efficacy of contrast cryolipolysis for subcutaneous-fat reduction. Contrast cryolipolysis mixes the principles of conventional cryolipolysis and periods of heating in accordance with the contrast lipocryolysis process. Twenty-one subjects aged 34 ± 9 years were treated with contrast cryolipolysis in the regions of abdomen and flanks through the Polarys® device. Anthropometry, standardized photographs, measurements with a skinfold caliper, and diagnostic ultrasounds were performed at the baseline and during follow-ups at 30, 60, and 90 days after the treatment. The safety assessments included laboratory testing and monitoring of the adverse events. The level of significance for all tests was set at P < 0.05. No significant differences in weight and body mass index were found. The waist measurements at the baseline and 30-day follow-up had significant differences, as did the measurements at the 30-day and 60-day follow-ups. The skinfold and ultrasound measurements were significantly reduced in the treated areas in all the time points compared to the baseline. The laboratory results showed no significant changes from baseline. Temporary adverse effects were resolved spontaneously. This study confirmed that contrast cryolipolysis is safe and effective in reducing the fat layer and improving body contouring.http://dx.doi.org/10.1155/2018/5276528
spellingShingle Marília Bueno Savacini
Débora Tazinaffo Bueno
Ana Carolina Souza Molina
Ana Caroline Almeida Lopes
Caroline Nogueira Silva
Renata Gomes Moreira
Stephani Almeida
Renata Michelini Guidi
Estela Sant’Ana
Richard Eloin Liebano
Effectiveness and Safety of Contrast Cryolipolysis for Subcutaneous-Fat Reduction
Dermatology Research and Practice
title Effectiveness and Safety of Contrast Cryolipolysis for Subcutaneous-Fat Reduction
title_full Effectiveness and Safety of Contrast Cryolipolysis for Subcutaneous-Fat Reduction
title_fullStr Effectiveness and Safety of Contrast Cryolipolysis for Subcutaneous-Fat Reduction
title_full_unstemmed Effectiveness and Safety of Contrast Cryolipolysis for Subcutaneous-Fat Reduction
title_short Effectiveness and Safety of Contrast Cryolipolysis for Subcutaneous-Fat Reduction
title_sort effectiveness and safety of contrast cryolipolysis for subcutaneous fat reduction
url http://dx.doi.org/10.1155/2018/5276528
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