Acute hemorrhagic leukoencephalitis mimicking herpes simplex encephalitis: case report
Acute hemorrhagic leukoencephalitis (AHLE) is a more severe form of acute disseminated encephalomyelities (ADEM) characterized by a fulminant clinical course and the presence of hemorrhagic necrosis of the white matter. We report the case of a 57-year-old woman who developed delirium following a res...
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| Format: | Article |
| Language: | English |
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Thieme Revinter Publicações
2004-03-01
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| Series: | Arquivos de Neuro-Psiquiatria |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2004000100024&tlng=en |
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| author | Henrique Milhomem Martins Antônio Lúcio Teixeira-Jr Marco Aurélio Lana-Peixoto |
| author_facet | Henrique Milhomem Martins Antônio Lúcio Teixeira-Jr Marco Aurélio Lana-Peixoto |
| author_sort | Henrique Milhomem Martins |
| collection | DOAJ |
| description | Acute hemorrhagic leukoencephalitis (AHLE) is a more severe form of acute disseminated encephalomyelities (ADEM) characterized by a fulminant clinical course and the presence of hemorrhagic necrosis of the white matter. We report the case of a 57-year-old woman who developed delirium following a respiratory infection. Magnetic resonance imaging of the brain disclosed signal abnormalities in the frontal and temporal lobes, usually found in herpes simplex encephalitis (HSE). Gram stain, India ink and acid-fast bacilli staining were all negative in CSF as was a polymerase chain reaction (PCR) for herpes simplex virus. A diagnosis of AHLE was made and the patient was treated with IV methylprednisolone 1g/day for 5 days. Despite treatment, the patient developed several neurological sequelae compatible with the severity of her illness. |
| format | Article |
| id | doaj-art-eece3835b5af4d2d9609d0abb04bd060 |
| institution | OA Journals |
| issn | 1678-4227 |
| language | English |
| publishDate | 2004-03-01 |
| publisher | Thieme Revinter Publicações |
| record_format | Article |
| series | Arquivos de Neuro-Psiquiatria |
| spelling | doaj-art-eece3835b5af4d2d9609d0abb04bd0602025-08-20T02:04:58ZengThieme Revinter PublicaçõesArquivos de Neuro-Psiquiatria1678-42272004-03-01621139143Acute hemorrhagic leukoencephalitis mimicking herpes simplex encephalitis: case reportHenrique Milhomem Martins0Antônio Lúcio Teixeira-Jr1Marco Aurélio Lana-Peixoto2Federal University of Minas GeraisFederal University of Minas GeraisFederal University of Minas GeraisAcute hemorrhagic leukoencephalitis (AHLE) is a more severe form of acute disseminated encephalomyelities (ADEM) characterized by a fulminant clinical course and the presence of hemorrhagic necrosis of the white matter. We report the case of a 57-year-old woman who developed delirium following a respiratory infection. Magnetic resonance imaging of the brain disclosed signal abnormalities in the frontal and temporal lobes, usually found in herpes simplex encephalitis (HSE). Gram stain, India ink and acid-fast bacilli staining were all negative in CSF as was a polymerase chain reaction (PCR) for herpes simplex virus. A diagnosis of AHLE was made and the patient was treated with IV methylprednisolone 1g/day for 5 days. Despite treatment, the patient developed several neurological sequelae compatible with the severity of her illness.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2004000100024&tlng=enacute disseminated encephalomyelitisacute hemorrhagic leukoencephalitisherpes simplex virus encephalitis |
| spellingShingle | Henrique Milhomem Martins Antônio Lúcio Teixeira-Jr Marco Aurélio Lana-Peixoto Acute hemorrhagic leukoencephalitis mimicking herpes simplex encephalitis: case report Arquivos de Neuro-Psiquiatria acute disseminated encephalomyelitis acute hemorrhagic leukoencephalitis herpes simplex virus encephalitis |
| title | Acute hemorrhagic leukoencephalitis mimicking herpes simplex encephalitis: case report |
| title_full | Acute hemorrhagic leukoencephalitis mimicking herpes simplex encephalitis: case report |
| title_fullStr | Acute hemorrhagic leukoencephalitis mimicking herpes simplex encephalitis: case report |
| title_full_unstemmed | Acute hemorrhagic leukoencephalitis mimicking herpes simplex encephalitis: case report |
| title_short | Acute hemorrhagic leukoencephalitis mimicking herpes simplex encephalitis: case report |
| title_sort | acute hemorrhagic leukoencephalitis mimicking herpes simplex encephalitis case report |
| topic | acute disseminated encephalomyelitis acute hemorrhagic leukoencephalitis herpes simplex virus encephalitis |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2004000100024&tlng=en |
| work_keys_str_mv | AT henriquemilhomemmartins acutehemorrhagicleukoencephalitismimickingherpessimplexencephalitiscasereport AT antoniolucioteixeirajr acutehemorrhagicleukoencephalitismimickingherpessimplexencephalitiscasereport AT marcoaureliolanapeixoto acutehemorrhagicleukoencephalitismimickingherpessimplexencephalitiscasereport |